TCERG1

TCERG1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DK7, 2DOD, 2DOE, 2DOF, 2E71, 2KIQ, 2KIS, 2MW9, 2MWA, 2MWB, 2MWD, 2MWF, 2NNT, 3HFH, 3Q1I, 4FQG, 2N4R, 2N4S, 2N4T, 2N4U, 2N4V, 2N4W
Dynodwyr
Cyfenwau	TCERG1, CA150, TAF2S, Urn1, transcription elongation regulator 1
Dynodwyr allanol	OMIM: 605409 HomoloGene: 4879 GeneCards: TCERG1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001105 transcription coactivator activity • GO:0001106 transcription corepressor activity • proline-rich region binding • GO:0001948, GO:0016582 protein binding • RNA binding • identical protein binding • RNA polymerase binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • transcription, DNA-templated • positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10915	n/a
Ensembl	ENSG00000113649	n/a
UniProt	O14776	n/a
RefSeq (mRNA)	NM_001040006 NM_006706 NM_001382548	n/a
RefSeq (protein)	NP_001035095 NP_006697 NP_001369477	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TCERG1 yw TCERG1 a elwir hefyd yn Transcription elongation regulator 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TCERG1.

• Urn1
• CA150
• TAF2S

Llyfryddiaeth

• "Differential effects of sumoylation on transcription and alternative splicing by transcription elongation regulator 1 (TCERG1). ". J Biol Chem. 2010. PMID 20215116.
• "Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays. ". J Mol Biol. 2009. PMID 19715701.
• "The in vivo dynamics of TCERG1, a factor that couples transcriptional elongation with splicing. ". RNA. 2016. PMID 26873599.
• "Specific interaction of the transcription elongation regulator TCERG1 with RNA polymerase II requires simultaneous phosphorylation at Ser2, Ser5, and Ser7 within the carboxyl-terminal domain repeat. ". J Biol Chem. 2013. PMID 23436654.
• "The FF4 and FF5 domains of transcription elongation regulator 1 (TCERG1) target proteins to the periphery of speckles.". J Biol Chem. 2012. PMID 22453921.