TAF13

TAF13
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BH8, 1BH9
Dynodwyr
Cyfenwau	TAF13, TAF(II)18, TAF2K, TAFII-18, TAFII18, TATA-box binding protein associated factor 13, MRT60
Dynodwyr allanol	OMIM: 600774 HomoloGene: 4126 GeneCards: TAF13
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • protein C-terminus binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • DNA binding • GO:0001104 transcription coregulator activity Cydrannau o'r gell • nucleolus • transcription factor TFIID complex • cnewyllyn cell • nucleoplasm Prosesau biolegol • transcription initiation from RNA polymerase II promoter • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • transcription, DNA-templated • DNA-templated transcription, initiation • snRNA transcription by RNA polymerase II • regulation of signal transduction by p53 class mediator • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6884	n/a
Ensembl	ENSG00000197780	n/a
UniProt	Q15543	n/a
RefSeq (mRNA)	NM_005645	n/a
RefSeq (protein)	NP_005636	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TAF13 yw TAF13 a elwir hefyd yn TATA-box binding protein associated factor 13 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TAF13.

• MRT60
• TAF2K
• TAFII18
• TAFII-18
• TAF(II)18

Llyfryddiaeth

• "Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID. ". EMBO J. 1995. PMID 7729427.
• "Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA. ". Nature. 1997. PMID 9311784.
• "Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly. ". Am J Hum Genet. 2017. PMID 28257693.
• "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family. ". Cell. 1998. PMID 9695952.
• "EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.". Mol Cell Biol. 1998. PMID 9488465.