SYN1

SYN1
Dynodwyr
Cyfenwau	SYN1, SYN1a, SYN1b, SYNI, Synapsin I, MRX50, EPILX
Dynodwyr allanol	OMIM: 313440 HomoloGene: 48483 GeneCards: SYN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • calcium-dependent protein binding • catalytic activity • GO:0001948, GO:0016582 protein binding • actin binding • ATP binding • protein kinase binding Cydrannau o'r gell • cytosol • Golgi apparatus • GO:0097483, GO:0097481 postsynaptic density • synaptic vesicle • myelin sheath • synapse • synaptic vesicle membrane • presynaptic active zone • axon • cell junction • terminal bouton • dendrite • intracellular organelle • synaptonemal complex • anchored component of synaptic vesicle membrane • presynapse • Cytosgerbwd • Schaffer collateral - CA1 synapse • extrinsic component of synaptic vesicle membrane Prosesau biolegol • regulation of neurotransmitter secretion • regulation of synaptic vesicle exocytosis • GO:0010554 neurotransmitter secretion • chemical synaptic transmission • synaptic vesicle clustering • neuron development • synapse organization • regulation of synaptic vesicle cycle • synaptic vesicle cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6853	n/a
Ensembl	ENSG00000008056	n/a
UniProt	P17600	n/a
RefSeq (mRNA)	NM_133499 NM_006950	n/a
RefSeq (protein)	NP_008881 NP_598006	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SYN1 yw SYN1 a elwir hefyd yn Synapsin I (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp11.3-p11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SYN1.

• SYNI
• SYN1a
• SYN1b

Llyfryddiaeth

• "Human synapsin I mediates the function of nuclear respiratory factor 1 in neurite outgrowth in neuroblastoma IMR-32 cells. ". J Neurosci Res. 2009. PMID 19301426.
• "Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy. ". J Med Genet. 2004. PMID 14985377.
• "Increased synapsin I expression in cerebral malaria. ". Int J Clin Exp Pathol. 2015. PMID 26823711.
• "Development of a high-throughput AlphaScreen assay for modulators of synapsin I phosphorylation in primary neurons. ". J Biomol Screen. 2014. PMID 24088370.
• "The C allele of synonymous SNP (rs1142636, Asn170Asn) in SYN1 is a risk factor for the susceptibility of Korean female schizophrenia.". Synapse. 2012. PMID 22807112.