SWAP70

SWAP70
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DN6
Dynodwyr
Cyfenwau	SWAP70, SWAP-70, HSPC321, SWAP switching B-cell complex 70kDa subunit, SWAP switching B-cell complex subunit 70, switching B-cell complex subunit switching B cell complex subunit SWAP70
Dynodwyr allanol	OMIM: 604762 HomoloGene: 7557 GeneCards: SWAP70
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • calcium ion binding • GO:0001948, GO:0016582 protein binding • ATP binding • cadherin binding Cydrannau o'r gell • cell projection • bilen • Cellbilen • Cytosgerbwd • cnewyllyn cell • lamellipodium • cytoplasm Prosesau biolegol • positive regulation of cytosolic calcium ion concentration • positive regulation of mast cell chemotaxis • negative regulation of peptidyl-serine dephosphorylation • negative regulation of actin filament depolymerization • actin filament bundle assembly • regulation of protein localization • regulation of actin polymerization or depolymerization • somatic cell DNA recombination • isotype switching • positive regulation of actin filament bundle assembly • negative regulation of cell-cell adhesion mediated by integrin Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23075	n/a
Ensembl	ENSG00000133789	n/a
UniProt	Q9UH65	n/a
RefSeq (mRNA)	NM_001297714 NM_015055	n/a
RefSeq (protein)	NP_001284643 NP_055870	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SWAP70 yw SWAP70 a elwir hefyd yn Switch-associated protein 70 a Switching B-cell complex subunit SWAP70 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11p15.4.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SWAP70.

• HSPC321
• SWAP-70

Llyfryddiaeth

• "Expression and localization of SWAP-70 in human fetomaternal interface and placenta during tubal pregnancy and normal placentation. ". J Histochem Cytochem. 2007. PMID 17371938.
• "Diagnostic surface expression of SWAP-70 on HIV-1 infected T cells. ". Microbiol Immunol. 2006. PMID 16547421.
• "SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. ". Cell Rep. 2016. PMID 27806292.
• "Switch-associated protein 70 antibodies in multiple sclerosis: relationship between increased serum levels and clinical relapse. ". Inflamm Res. 2012. PMID 22728961.
• "Membrane-induced alteration of the secondary structure in the SWAP-70 pleckstrin homology domain.". J Biochem. 2012. PMID 22247562.