SULT1A1

SULT1A1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1LS6, 1Z28, 2D06, 3QVU, 3QVV, 3U3J, 3U3K, 3U3M, 3U3O, 3U3R, 4GRA
Dynodwyr
Cyfenwau	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1, sulfotransferase family 1A member 1, ts-PST, P-PST 1
Dynodwyr allanol	OMIM: 171150 HomoloGene: 134950 GeneCards: SULT1A1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • sulfotransferase activity • steroid sulfotransferase activity • flavonol 3-sulfotransferase activity • GO:0001948, GO:0016582 protein binding • aryl sulfotransferase activity Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • steroid metabolic process • amine metabolic process • catecholamine metabolic process • estrogen metabolic process • sulfation • lipid metabolism • flavonoid metabolic process • xenobiotic metabolic process • ethanol catabolic process • 3'-phosphoadenosine 5'-phosphosulfate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6817	n/a
Ensembl	ENSG00000196502	n/a
UniProt	P50225	n/a
RefSeq (mRNA)	NM_177536 NM_001055 NM_177529 NM_177530 NM_177534 NM_001394421 NM_001394422 NM_001394423 NM_001394424 NM_001394425	n/a
RefSeq (protein)	NP_001046 NP_803565 NP_803566 NP_803878 NP_803880	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SULT1A1 yw SULT1A1 a elwir hefyd yn Sulfotransferase family 1A member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16p11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SULT1A1.

• PST
• STP
• STP1
• P-PST
• ST1A1
• ST1A3
• TSPST1
• HAST1/HAST2

Llyfryddiaeth

• "Cytosolic sulfotransferase 1A1 regulates HIV-1 minus-strand DNA elongation in primary human monocyte-derived macrophages. ". Virol J. 2016. PMID 26906565.
• "Sulfotransferase 1A1 Substrate Selectivity: A Molecular Clamp Mechanism. ". Biochemistry. 2015. PMID 26340710.
• "Relationship of SULT1A1 copy number variation with estrogen metabolism and human health. ". J Steroid Biochem Mol Biol. 2017. PMID 28867356.
• "Isozyme Specific Allosteric Regulation of Human Sulfotransferase 1A1. ". Biochemistry. 2016. PMID 27356022.
• "Effects of SULT1A1 Copy Number Variation on Estrogen Concentration and Tamoxifen-Associated Adverse Drug Reactions in Premenopausal Thai Breast Cancer Patients: A Preliminary Study.". Asian Pac J Cancer Prev. 2016. PMID 27221864.