STX1B

STX1B
Dynodwyr
Cyfenwau	STX1B, STX1B1, STX1B2, GEFSP9, syntaxin 1B
Dynodwyr allanol	OMIM: 601485 HomoloGene: 69375 GeneCards: STX1B
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• SNAP receptor activity; • protein kinase binding; • signaling receptor binding; • SNARE binding; • protein domain specific binding;
Cydrannau o'r gell	• integral component of membrane; • cytosol; • bilen; • synaptic vesicle; • Cellbilen; • spindle; • microtubule organizing center; • SNARE complex; • Cytosgerbwd; • nuclear lamina; • cnewyllyn cell; • nucleoplasm; • centrosome; • cytoplasm; • presynaptic membrane; • presynapse; • presynaptic active zone membrane; • axon; • neuromuscular junction; • endomembrane system;
Prosesau biolegol	• synaptic vesicle docking; • spontaneous neurotransmitter secretion; • positive regulation of neurotransmitter secretion; • regulation of exocytosis; • vesicle docking; • positive regulation of excitatory postsynaptic potential; • regulation of gene expression; • protein transport; • intracellular protein transport; • neurotransmitter transport; • vesicle-mediated transport; • regulation of synaptic vesicle priming; • negative regulation of neuron projection development; • regulation of synaptic activity; • vesicle docking involved in exocytosis; • calcium ion-regulated exocytosis of neurotransmitter; • protein localization to membrane; • negative regulation of synaptic vesicle recycling; • positive regulation of spontaneous neurotransmitter secretion; • negative regulation of macropinocytosis; • synaptic vesicle fusion to presynaptic active zone membrane; • exocytic insertion of neurotransmitter receptor to postsynaptic membrane; • synaptic vesicle exocytosis; • exocytosis; • vesicle fusion;
	Sources:Amigo / QuickGO
Orthologau
	112755
	n/a
	ENSG00000099365
	n/a
	P61266
	n/a
	NM_052874
	n/a
	NP_443106
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STX1B yw STX1B a elwir hefyd yn Syntaxin 1B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16p11.2.^[2]

Cyfystyron[golygu | golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STX1B.

GEFSP9
STX1B1
STX1B2

Llyfryddiaeth[golygu | golygu cod]

"The RIT2 and STX1B polymorphisms are associated with Parkinson's disease. ". Parkinsonism Relat Disord. 2015. PMID 25534083.
"Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. ". Nat Genet. 2014. PMID 25362483.
"Motor cortex excitability in seizure-free STX1B mutation carriers with a history of epilepsy and febrile seizures. ". Clin Neurophysiol. 2017. PMID 29101845.
"Assignment of the human syntaxin 1B gene (STX) to chromosome 16p11.2 by fluorescence in situ hybridization. ". Genomics. 1996. PMID 8884284.
"Characterization of a presynaptic glutamate receptor.". Science. 1993. PMID 8105537.

Cyfeiriadau[golygu | golygu cod]

[1] "Human PubMed Reference:".

[2] STX1B - Cronfa NCBI

[1]

[2]