STK10

STK10
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2J7T, 4AOT, 4BC6, 4EQU, 4USD, 4USE, 5AJQ
Dynodwyr
Cyfenwau	STK10, LOK, PRO2729, serine/threonine kinase 10
Dynodwyr allanol	OMIM: 603919 HomoloGene: 38122 GeneCards: STK10
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • protein homodimerization activity • kinase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • ATP binding • protein serine/threonine kinase activity Cydrannau o'r gell • cytoplasm • bilen • extracellular exosome • Cellbilen • specific granule membrane Prosesau biolegol • lymphocyte aggregation • phosphorylation • regulation of lymphocyte migration • protein autophosphorylation • cell cycle • protein phosphorylation • neutrophil degranulation • regulation of mitotic cell cycle • GO:0072468 signal transduction • stress-activated protein kinase signaling cascade • activation of protein kinase activity • regulation of apoptotic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6793	n/a
Ensembl	ENSG00000072786	n/a
UniProt	O94804	n/a
RefSeq (mRNA)	NM_005990	n/a
RefSeq (protein)	NP_005981	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STK10 yw STK10 a elwir hefyd yn Serine/threonine kinase 10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q35.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STK10.

• LOK
• PRO2729

Llyfryddiaeth

• "Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults. ". Genes Chromosomes Cancer. 2006. PMID 16175573.
• "Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells. ". Biochem J. 2002. PMID 11903060.
• "STK10 missense mutations associated with anti-apoptotic function. ". Oncol Rep. 2013. PMID 23842845.
• "Variations in the STK10 gene and possible associations with aspirin-intolerant asthma in a Korean population. ". J Investig Allergol Clin Immunol. 2011. PMID 21905501.
• "Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism.". Elife. 2017. PMID 28430576.