STEAP3

STEAP3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2VNS, 2VQ3
Dynodwyr
Cyfenwau	STEAP3, AHMIO2, STMP3, TSAP6, dudlin-2, dudulin-2, pHyde, STEAP3 metalloreductase
Dynodwyr allanol	OMIM: 609671 HomoloGene: 10084 GeneCards: STEAP3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • GO:0001948, GO:0016582 protein binding • ferric-chelate reductase (NADPH) activity • metal ion binding • cupric reductase activity • oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor • identical protein binding Cydrannau o'r gell • integral component of membrane • multivesicular body • endosome • endosome membrane • bilen • integral component of plasma membrane • cytoplasm • Cellbilen Prosesau biolegol • GO:0097285 apoptotic process • protein secretion • cell cycle • iron ion homeostasis • copper ion import • cludo ïon • transferrin transport • regulation of apoptotic process • iron ion import across cell outer membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55240	n/a
Ensembl	ENSG00000115107	n/a
UniProt	Q658P3	n/a
RefSeq (mRNA)	NM_001008410 NM_018234 NM_138637 NM_182915	n/a
RefSeq (protein)	NP_001008410 NP_060704 NP_619543 NP_878919	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STEAP3 yw STEAP3 a elwir hefyd yn STEAP3 metalloreductase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q14.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STEAP3.

• STMP3
• TSAP6
• pHyde
• AHMIO2
• dudlin-2
• dudulin-2

Llyfryddiaeth

• "The STEAP protein family: versatile oxidoreductases and targets for cancer immunotherapy with overlapping and distinct cellular functions. ". Biol Cell. 2012. PMID 22804687.
• "STEAP proteins: from structure to applications in cancer therapy. ". Mol Cancer Res. 2012. PMID 22522456.
• "TSAP6 is a novel candidate marker of poor survival in metastatic high-grade serous carcinoma. ". Hum Pathol. 2017. PMID 27825812.
• "Human STEAP3 mutations with no phenotypic red cell changes. ". Blood. 2016. PMID 26675350.
• "Characterization of a single b-type heme, FAD, and metal binding sites in the transmembrane domain of six-transmembrane epithelial antigen of the prostate (STEAP) family proteins.". J Biol Chem. 2015. PMID 26205815.