STAM

STAM
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2L0A, 3F1I, 3LDZ
Dynodwyr
Cyfenwau	STAM, STAM-1, STAM1, Signal transducing adaptor molecule
Dynodwyr allanol	OMIM: 601899 HomoloGene: 37788 GeneCards: STAM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • ubiquitin-like protein ligase binding Cydrannau o'r gell • cytoplasm • cytosol • endosome • early endosome membrane • bilen • ESCRT-0 complex Prosesau biolegol • negative regulation of epidermal growth factor receptor signaling pathway • regulation of extracellular exosome assembly • multivesicular body assembly • endosomal transport • protein transport • positive regulation of exosomal secretion • intracellular protein transport • GO:0072468 signal transduction • positive regulation of signal transduction • macroautophagy • protein deubiquitination • membrane organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8027	n/a
Ensembl	ENSG00000136738	n/a
UniProt	Q92783	n/a
RefSeq (mRNA)	NM_003473 NM_001324282 NM_001324283 NM_001324284 NM_001324285 NM_001324286 NM_001324287 NM_001324288 NM_001324289	n/a
RefSeq (protein)	NP_001311211 NP_001311212 NP_001311213 NP_001311214 NP_001311215 NP_001311216 NP_001311217 NP_001311218 NP_003464	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STAM yw STAM a elwir hefyd yn Signal transducing adaptor molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10p12.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STAM.

• STAM1
• STAM-1

Llyfryddiaeth

• "Identification of a novel ubiquitin binding site of STAM1 VHS domain by NMR spectroscopy. ". FEBS Lett. 2009. PMID 19111546.
• "AMSH is an endosome-associated ubiquitin isopeptidase. ". J Cell Biol. 2004. PMID 15314065.
• "Backbone 1H, 13C, and 15N assignments for the tandem ubiquitin binding domains of signal transducing adapter molecule 1. ". Biomol NMR Assign. 2011. PMID 20927613.
• "Conformational and dynamic changes at the interface contribute to ligand binding by ubiquitin. ". Biochemistry. 2012. PMID 23035694.
• "Solution structure of UIM and interaction of tandem ubiquitin binding domains in STAM1 with ubiquitin.". Biochem Biophys Res Commun. 2011. PMID 21187078.