SRSF7

SRSF7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HVZ
Dynodwyr
Cyfenwau	SRSF7, 9G8, AAG3, SFRS7, serine/arginine-rich splicing factor 7, serine and arginine rich splicing factor 7
Dynodwyr allanol	OMIM: 600572 HomoloGene: 134446 GeneCards: SRSF7
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • zinc ion binding • metal ion binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • RNA binding • protein domain specific binding Cydrannau o'r gell • cytoplasm • nucleoplasm • extracellular exosome • cnewyllyn cell • nuclear speck Prosesau biolegol • mRNA splicing, via spliceosome • termination of RNA polymerase II transcription • mRNA transport • mRNA processing • mRNA export from nucleus • negative regulation of mRNA splicing, via spliceosome • mRNA 3'-end processing • RNA export from nucleus • RNA splicing • cellular response to leukemia inhibitory factor • GO:0015915 transport • regulation of alternative mRNA splicing, via spliceosome • mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6432	n/a
Ensembl	ENSG00000115875	n/a
UniProt	Q16629	n/a
RefSeq (mRNA)	NM_001031684 NM_001195446 NM_006276 NM_001363802	n/a
RefSeq (protein)	NP_001026854 NP_001182375 NP_001350731	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SRSF7 yw SRSF7 a elwir hefyd yn Serine and arginine rich splicing factor 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SRSF7.

• 9G8
• AAG3
• SFRS7

Llyfryddiaeth

• "The gene encoding human splicing factor 9G8. Structure, chromosomal localization, and expression of alternatively processed transcripts. ". J Biol Chem. 1995. PMID 7629084.
• "Serine/arginine-rich splicing factor 7 regulates p21-dependent growth arrest in colon cancer cells. ". J Med Invest. 2016. PMID 27644562.
• "The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element. ". J Biol Chem. 2007. PMID 17513303.
• "SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations. ". Mol Cell Neurosci. 2007. PMID 17137791.
• "Alternative splicing of intron 3 of the serine/arginine-rich protein 9G8 gene. Identification of flanking exonic splicing enhancers and involvement of 9G8 as a trans-acting factor.". J Biol Chem. 2001. PMID 11096110.