SRSF3

SRSF3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2I38
Dynodwyr
Cyfenwau	SRSF3, SFRS3, SRp20, serine/arginine-rich splicing factor 3, serine and arginine rich splicing factor 3
Dynodwyr allanol	OMIM: 603364 HomoloGene: 55708 GeneCards: SRSF3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • sequence-specific mRNA binding • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • cnewyllyn cell • cytoplasm • nucleoplasm • nuclear speck Prosesau biolegol • termination of RNA polymerase II transcription • mRNA 3'-end processing • mRNA splicing, via spliceosome • mRNA export from nucleus • mRNA transport • mRNA processing • RNA splicing • regulation of mRNA splicing, via spliceosome • RNA export from nucleus • GO:0015915 transport • regulation of alternative mRNA splicing, via spliceosome • mRNA cis splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6428	n/a
Ensembl	ENSG00000112081	n/a
UniProt	P84103	n/a
RefSeq (mRNA)	NM_003017	n/a
RefSeq (protein)	NP_003008	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SRSF3 yw SRSF3 a elwir hefyd yn Serine and arginine rich splicing factor 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.31-p21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SRSF3.

• SFRS3
• SRp20

Llyfryddiaeth

• "Viral proteinase requirements for the nucleocytoplasmic relocalization of cellular splicing factor SRp20 during picornavirus infections. ". J Virol. 2013. PMID 23255796.
• "Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer's disease. ". J Neurochem. 2012. PMID 22788679.
• "Expression of SRSF3 is Correlated with Carcinogenesis and Progression of Oral Squamous Cell Carcinoma. ". Int J Med Sci. 2016. PMID 27429590.
• "A genome landscape of SRSF3-regulated splicing events and gene expression in human osteosarcoma U2OS cells. ". Nucleic Acids Res. 2016. PMID 26704980.
• "Serine/arginine-rich splicing factor 3 (SRSF3) regulates homologous recombination-mediated DNA repair.". Mol Cancer. 2015. PMID 26282282.