SRPK1

SRPK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WAK, 1WBP, 3BEG, 4WUA
Dynodwyr
Cyfenwau	SRPK1, SFRSK1, SRSF protein kinase 1
Dynodwyr allanol	OMIM: 601939 HomoloGene: 110962 GeneCards: SRPK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • protein kinase activity • nucleotide binding • kinase activity • protein serine/threonine kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • magnesium ion binding • RNA binding Cydrannau o'r gell • cytoplasm • intracellular membrane-bounded organelle • nuclear matrix • Cellbilen • Reticwlwm endoplasmig • cnewyllyn cell • cytosol Prosesau biolegol • cell differentiation • GO:0007243 intracellular signal transduction • phosphorylation • regulation of mRNA processing • chromosome segregation • mRNA processing • regulation of mRNA splicing, via spliceosome • protein phosphorylation • negative regulation of viral genome replication • RNA splicing • positive regulation of viral genome replication • innate immune response • GO:0022415 viral process • GO:0035093 sperm DNA condensation • spliceosomal complex assembly • regulation of gene expression Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6732	n/a
Ensembl	n/a	n/a
UniProt	Q96SB4	n/a
RefSeq (mRNA)	NM_003137	n/a
RefSeq (protein)	NP_003128	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SRPK1 yw SRPK1 a elwir hefyd yn SRSF protein kinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SRPK1.

• SFRSK1

Llyfryddiaeth

• "Serine-arginine protein kinase 1 (SRPK1), a determinant of angiogenesis, is upregulated in prostate cancer and correlates with disease stage and invasion. ". J Clin Pathol. 2016. PMID 26500332.
• "Serine-arginine protein kinase 1 is associated with hepatocellular carcinoma progression and poor patient survival. ". Tumour Biol. 2016. PMID 26201897.
• "Knockdown of Serine-Arginine Protein Kinase 1 Inhibits the Growth and Migration in Renal Cell Carcinoma Cells. ". Oncol Res. 2017. PMID 27662590.
• "Expression of SRPK1 in gliomas and its role in glioma cell lines viability. ". Tumour Biol. 2016. PMID 26738865.
• "Up-regulation of SRPK1 in non-small cell lung cancer promotes the growth and migration of cancer cells.". Tumour Biol. 2016. PMID 26666824.