SP4

SP4
Dynodwyr
Cyfenwau	SP4, HF1B, SPR-1, Sp4 transcription factor
Dynodwyr allanol	OMIM: 600540 HomoloGene: 2341 GeneCards: SP4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001105 transcription coactivator activity • GO:0001948, GO:0016582 protein binding • metal ion binding • sequence-specific DNA binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytosol Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6671	n/a
Ensembl	ENSG00000105866	n/a
UniProt	Q02446	n/a
RefSeq (mRNA)	NM_003112 NM_001326542 NM_001326543	n/a
RefSeq (protein)	NP_001313471 NP_001313472 NP_003103	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SP4 yw SP4 a elwir hefyd yn Sp4 transcription factor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7p15.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SP4.

• HF1B
• SPR-1

Llyfryddiaeth

• "Genetics and expression analysis of the specificity protein 4 gene (SP4) in patients with Alzheimer's disease and frontotemporal lobar degeneration. ". J Alzheimers Dis. 2012. PMID 22614877.
• "The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium. ". Bipolar Disord. 2011. PMID 22017217.
• "Role played by the SP4 gene in schizophrenia and major depressive disorder in the Han Chinese population. ". Br J Psychiatry. 2016. PMID 26450579.
• "Transcription factor SP4 phosphorylation is altered in the postmortem cerebellum of bipolar disorder and schizophrenia subjects. ". Eur Neuropsychopharmacol. 2015. PMID 26049820.
• "Phosphorylation of transcription factor specificity protein 4 is increased in peripheral blood mononuclear cells of first-episode psychosis.". PLoS One. 2015. PMID 25915526.