SORD

SORD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PL8, 1PL6, 1PL7
Dynodwyr
Cyfenwau	SORD, HEL-S-95n, SORD1, sorbitol dehydrogenase, XDH, RDH, SDH, SORDD
Dynodwyr allanol	OMIM: 182500 HomoloGene: 56080 GeneCards: SORD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • NAD binding • zinc ion binding • metal ion binding • L-iditol 2-dehydrogenase activity • oxidoreductase activity • D-xylulose reductase activity • carbohydrate binding • identical protein binding • (R,R)-butanediol dehydrogenase activity • ribitol 2-dehydrogenase activity Cydrannau o'r gell • cytosol • cell projection • bilen • mitochondrial membranes • cilium • mitocondria • motile cilium • extracellular exosome • extracellular space Prosesau biolegol • flagellated sperm motility • response to cadmium ion • response to copper ion • sorbitol catabolic process • fructose biosynthetic process • glucuronate catabolic process to xylulose 5-phosphate • response to osmotic stress • L-xylitol metabolic process • response to nutrient levels • glucose metabolic process • L-xylitol catabolic process • response to hormone • sorbitol metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6652	n/a
Ensembl	ENSG00000140263	n/a
UniProt	Q00796	n/a
RefSeq (mRNA)	NM_003104	n/a
RefSeq (protein)	NP_003095	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SORD yw SORD a elwir hefyd yn Sorbitol dehydrogenase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SORD.

• SORD1
• HEL-S-95n

Llyfryddiaeth

• "Polyol pathway in human epididymis and semen. ". J Androl. 2006. PMID 16278369.
• "Expression, purification and preliminary crystallographic analysis of human sorbitol dehydrogenase. ". Acta Crystallogr D Biol Crystallogr. 2003. PMID 12595725.
• "Association study of sorbitol dehydrogenase -888G>C polymorphism with type 2 diabetic retinopathy in Caucasian-Brazilians. ". Exp Eye Res. 2013. PMID 23850972.
• "Aldo-keto reductase and sorbitol dehydrogenase enzymes in Egyptian diabetic patients with and without proliferative diabetic retinopathy. ". Clin Exp Optom. 2013. PMID 23452182.
• "Sorbitol dehydrogenase expression is regulated by androgens in the human prostate.". Oncol Rep. 2010. PMID 20372835.