SNRPD1

SNRPD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1B34, 3CW1, 3PGW, 3S6N, 4F7U, 4PJO, 4V98, 4WZJ, 3JCR
Dynodwyr
Cyfenwau	SNRPD1, HsT2456, SMD1, SNRPD, Sm-D1, Small nuclear ribonucleoprotein D1, small nuclear ribonucleoprotein D1 polypeptide
Dynodwyr allanol	OMIM: 601063 HomoloGene: 107532 GeneCards: SNRPD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • U1 snRNP binding • RNA binding Cydrannau o'r gell • cytoplasm • SMN-Sm protein complex • cytosol • prespliceosome • catalytic step 2 spliceosome • spliceosomal tri-snRNP complex • U5 snRNP • U12-type spliceosomal complex • U2 snRNP • nucleoplasm • methylosome • precatalytic spliceosome • small nuclear ribonucleoprotein complex • pICln-Sm protein complex • spliceosomal complex • commitment complex • U4 snRNP • cnewyllyn cell • U1 snRNP • U4/U6 x U5 tri-snRNP complex • U2-type precatalytic spliceosome • U2-type catalytic step 2 spliceosome Prosesau biolegol • mRNA splicing, via spliceosome • GO:0033168, GO:0036404, GO:1902360 RNA processing • mRNA processing • spliceosomal complex assembly • RNA splicing • import into nucleus • spliceosomal snRNP assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6632	n/a
Ensembl	ENSG00000167088	n/a
UniProt	P62314	n/a
RefSeq (mRNA)	NM_006938 NM_001291916	n/a
RefSeq (protein)	NP_001278845 NP_008869	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNRPD1 yw SNRPD1 a elwir hefyd yn Small nuclear ribonucleoprotein D1 polypeptide (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNRPD1.

• SMD1
• SNRPD
• Sm-D1
• HsT2456

Llyfryddiaeth

• "The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies. ". J Biol Chem. 2000. PMID 10747894.
• "Molecular cloning of a cDNA encoding the human Sm-D autoantigen. ". Proc Natl Acad Sci U S A. 1988. PMID 3260384.
• "Association of cerebrospinal fluid anti-Sm antibodies with acute confusional state in systemic lupus erythematosus. ". Arthritis Res Ther. 2014. PMID 25273532.
• "Analysis of genes for human snRNP Sm-D1 protein and identification of the promoter sequence which shows segmental homology to the promoters of Sm-E and U1 snRNA genes. ". Gene. 1997. PMID 9168134.
• "Targeting the deregulated spliceosome core machinery in cancer cells triggers mTOR blockade and autophagy.". Cancer Res. 2013. PMID 23358685.