SNRNP200

SNRNP200
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2Q0Z, 4F91, 4F92, 4F93, 4KIT, 3JCR
Dynodwyr
Cyfenwau	SNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, small nuclear ribonucleoprotein U5 subunit 200
Dynodwyr allanol	OMIM: 601664 HomoloGene: 5859 GeneCards: SNRNP200
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GO:0008026 helicase activity • GO:0001948, GO:0016582 protein binding • identical protein binding • nucleic acid binding • hydrolase activity • ATP binding • RNA binding Cydrannau o'r gell • catalytic step 2 spliceosome • bilen • U5 snRNP • nucleoplasm • spliceosomal complex • cnewyllyn cell • U4/U6 x U5 tri-snRNP complex • post-mRNA release spliceosomal complex Prosesau biolegol • mRNA splicing, via spliceosome • mRNA processing • osteoblast differentiation • cis assembly of pre-catalytic spliceosome • RNA splicing • spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23020	n/a
Ensembl	ENSG00000144028	n/a
UniProt	O75643	n/a
RefSeq (mRNA)	NM_014014	n/a
RefSeq (protein)	NP_054733	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNRNP200 yw SNRNP200 a elwir hefyd yn Small nuclear ribonucleoprotein U5 subunit 200 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNRNP200.

• BRR2
• RP33
• HELIC2
• ASCC3L1
• U5-200KD

Llyfryddiaeth

• "Contribution of SNRNP200 sequence variations to retinitis pigmentosa. ". Eye (Lond). 2013. PMID 23887765.
• "Cell cycle abnormalities associated with differential perturbations of the human U5 snRNP associated U5-200kD RNA helicase. ". PLoS One. 2013. PMID 23637979.
• "Spliceosome SNRNP200 Promotes Viral RNA Sensing and IRF3 Activation of Antiviral Response. ". PLoS Pathog. 2016. PMID 27454487.
• "Mutations in the small nuclear riboprotein 200 kDa gene (SNRNP200) cause 1.6% of autosomal dominant retinitis pigmentosa. ". Mol Vis. 2013. PMID 24319334.
• "Retinitis pigmentosa mutations of SNRNP200 enhance cryptic splice-site recognition.". Hum Mutat. 2014. PMID 24302620.