SMG7

Oddi ar Wicipedia
Jump to navigation Jump to search
SMG7
Protein SMG7 PDB 1ya0.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauSMG7, C1orf16, EST1C, SGA56M, nonsense mediated mRNA decay factor, SMG7 nonsense mediated mRNA decay factor
Dynodwyr allanolOMIM: 610964 MGI: 2682334 HomoloGene: 32235 GeneCards: SMG7
Patrwm RNA pattern
PBB GE SMG7 217189 s at fs.png

PBB GE SMG7 201793 x at fs.png

PBB GE SMG7 201794 s at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001005507
NM_001160256
NM_001160257
NM_001359257

RefSeq (protein)

NP_001005507
NP_001153728
NP_001153729
NP_001346186

Lleoliad (UCSC)n/aChr : 152.84 – 152.9 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn SMG7 yw SMG7 a elwir hefyd yn Protein SMG7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q25.3.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SMG7.

  • EST1C
  • SGA56M
  • C1orf16

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. ". Ann Rheum Dis. 2016. PMID 26783109.
  • "SMG7 acts as a molecular link between mRNA surveillance and mRNA decay. ". Mol Cell. 2004. PMID 15546618.
  • "Frameshift Mutations of SMG7 Essential for Nonsense-Mediated mRNA Decay in Gastric and Colorectal Cancers. ". Pathol Oncol Res. 2017. PMID 27771886.
  • "Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates. ". RNA. 2017. PMID 28461625.
  • "Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.". RNA. 2017. PMID 27864472.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000042772 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. SMG7 - Cronfa NCBI