SLBP

SLBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2KJM, 4QOZ
Dynodwyr
Cyfenwau	SLBP, HBP, stem-loop binding protein
Dynodwyr allanol	OMIM: 602422 HomoloGene: 31389 GeneCards: SLBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • histone pre-mRNA DCP binding • histone pre-mRNA stem-loop binding • GO:0001948, GO:0016582 protein binding • mRNA binding • RNA binding • identical protein binding Cydrannau o'r gell • cytoplasm • histone pre-mRNA 3'end processing complex • nucleoplasm • cnewyllyn cell • nucleolus • cytosol • ribonucleoprotein complex Prosesau biolegol • termination of RNA polymerase II transcription • mRNA transport • mRNA 3'-end processing by stem-loop binding and cleavage • mRNA processing • mRNA export from nucleus • nuclear DNA replication • histone mRNA metabolic process • cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7884	n/a
Ensembl	ENSG00000163950	n/a
UniProt	Q14493 Q53XR2	n/a
RefSeq (mRNA)	NM_001306074 NM_001306075 NM_006527	n/a
RefSeq (protein)	NP_001293003 NP_001293004 NP_006518 NP_006518.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SLBP yw SLBP a elwir hefyd yn Histone RNA hairpin-binding protein a Stem-loop (Histone) binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4p16.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SLBP.

• HBP

Llyfryddiaeth

• "Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression. ". J Biol Chem. 2014. PMID 25266719.
• "Translation regulation and proteasome mediated degradation cooperate to keep stem-loop binding protein low in G1-phase. ". J Cell Biochem. 2014. PMID 24122909.
• "Nickel and cadmium-induced SLBP depletion: A potential pathway to metal mediated cellular transformation. ". PLoS One. 2017. PMID 28306745.
• "Stem-loop binding protein is a multifaceted cellular regulator of HIV-1 replication. ". J Clin Invest. 2016. PMID 27454292.
• "A Potential New Mechanism of Arsenic Carcinogenesis: Depletion of Stem-Loop Binding Protein and Increase in Polyadenylated Canonical Histone H3.1 mRNA.". Biol Trace Elem Res. 2015. PMID 25893362.