SIRPB1

SIRPB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D9C, 2JJU,%%s2JJV
Dynodwyr
Cyfenwau	SIRPB1, CD172b, SIRP-BETA-1, signal regulatory protein beta 1
Dynodwyr allanol	OMIM: 603889 HomoloGene: 82993 GeneCards: SIRPB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • Cellbilen • integral component of plasma membrane • bilen • secretory granule membrane • cell surface Prosesau biolegol • cell surface receptor signaling pathway • innate immune response • GO:0072468 signal transduction • neutrophil degranulation • positive regulation of cell-cell adhesion • positive regulation of phagocytosis • positive regulation of T cell activation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10326	n/a
Ensembl	ENSG00000101307	n/a
UniProt	O00241 Q5TFQ8	n/a
RefSeq (mRNA)	NM_001083910 NM_001135844 NM_006065 NM_001329157 NM_001330639	n/a
RefSeq (protein)	NP_001077379 NP_001129316 NP_001316086 NP_001317568 NP_006056 NP_001129316.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SIRPB1 yw SIRPB1 a elwir hefyd yn Signal-regulatory protein beta-1 a Signal-regulatory protein beta-1 isoform 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SIRPB1.

• CD172b
• SIRP-BETA-1

Llyfryddiaeth

• "Cutting edge: signal-regulatory protein beta 1 is a DAP12-associated activating receptor expressed in myeloid cells. ". J Immunol. 2000. PMID 10604985.
• "Association of signal-regulatory proteins beta with KARAP/DAP-12. ". Eur J Immunol. 2000. PMID 10940905.
• "SIRPB1 copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality. ". Genes Brain Behav. 2014. PMID 25039969.
• "Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease. ". Am J Pathol. 2009. PMID 19893026.
• "SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration.". J Biol Chem. 2005. PMID 16081415.