SH3GL3

SH3GL3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EW3, 2Z0V
Dynodwyr
Cyfenwau	SH3GL3, CNSA3, EEN-B2, HsT19371, SH3D2C, SH3P13, SH3 domain containing GRB2 like endophilin A3, SH3 domain containing GRB2 like 3, endophilin A3
Dynodwyr allanol	OMIM: 603362 HomoloGene: 37723 GeneCards: SH3GL3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • identical protein binding • lipid binding • protein C-terminus binding Cydrannau o'r gell • cytoplasm • endosome • early endosome • early endosome membrane • bilen • acrosomal vesicle • synapse • presynapse • postsynaptic endosome • glutamatergic synapse • postsynaptic density, intracellular component Prosesau biolegol • central nervous system development • endocytosis • GO:0072468 signal transduction • positive regulation of neuron differentiation • negative regulation of clathrin-dependent endocytosis • regulation of clathrin-dependent endocytosis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6457	n/a
Ensembl	ENSG00000140600	n/a
UniProt	Q99963	n/a
RefSeq (mRNA)	NM_001301108 NM_001301109 NM_003027 NM_001324182 NM_001324183 NM_001324184 NM_001324185 NM_001324186 NM_001324187	n/a
RefSeq (protein)	NP_001288037 NP_001288038 NP_001311111 NP_001311112 NP_001311113 NP_001311114 NP_001311115 NP_001311116 NP_003018	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SH3GL3 yw SH3GL3 a elwir hefyd yn SH3 domain containing GRB2 like 3, endophilin A3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SH3GL3.

• CNSA3
• EEN-B2
• SH3D2C
• SH3P13
• HsT19371

Llyfryddiaeth

• "Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes. ". Neuropathol Appl Neurobiol. 2012. PMID 21722156.
• "Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor. ". Proc Natl Acad Sci U S A. 1999. PMID 10535961.
• "Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor. ". J Biol Chem. 2003. PMID 12477732.
• "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates. ". Mol Cell. 1998. PMID 9809064.
• "Genome-wide analysis of aberrant DNA methylation for identification of potential biomarkers in colorectal cancer patients.". Asian Pac J Cancer Prev. 2012. PMID 22901147.