SH2D1A

SH2D1A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1D1Z, 1D4T, 1D4W, 1KA6, 1KA7, 1M27
Dynodwyr
Cyfenwau	SH2D1A, DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/XLP, XLPD, XLPD1, SH2 domain containing 1A
Dynodwyr allanol	OMIM: 300490 HomoloGene: 1762 GeneCards: SH2D1A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • cell-cell signaling • cellular defense response • innate immune response • humoral immune response • positive regulation of natural killer cell mediated cytotoxicity • adaptive immune response • immune system process • regulation of immune response • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4068	n/a
Ensembl	ENSG00000183918	n/a
UniProt	O60880	n/a
RefSeq (mRNA)	NM_002351 NM_001114937	n/a
RefSeq (protein)	NP_001108409 NP_002342	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SH2D1A yw SH2D1A a elwir hefyd yn SH2 domain containing 1A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xq25.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SH2D1A.

• LYP
• SAP
• XLP
• DSHP
• EBVS
• IMD5
• XLPD
• MTCP1
• XLPD1
• SAP/SH2D1A

Llyfryddiaeth

• "Skewed Invariant Natural Killer T (iNKT) Cells, Impaired iNKT:B Cell Help and Decreased SAP Expression in Blood Lymphocytes from Patients with Common Variable Immunodeficiency. ". Scand J Immunol. 2017. PMID 29083052.
• "X-linked Lymphoproliferative Disease Type 1 in a Patient With the p.Gly93Asp SH2D1A Gene Mutation and Hemophagocytic Lymphohistiocytosis. ". J Pediatr Hematol Oncol. 2017. PMID 28816794.
• "Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production. ". J Immunol. 2016. PMID 27183584.
• "Up-Regulation of LAT1 during Antiandrogen Therapy Contributes to Progression in Prostate Cancer Cells. ". J Urol. 2016. PMID 26682754.
• "Cerebral Vasculitis in X-linked Lymphoproliferative Disease Cured by Matched Unrelated Cord Blood Transplant.". J Clin Immunol. 2015. PMID 26433589.