SFTPD

SFTPD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1B08, 1M7L, 1PW9, 1PWB, 2GGU, 2GGX, 2ORJ, 2ORK, 2OS9, 2RIA, 2RIB, 2RIC, 2RID, 2RIE, 3DBZ, 3G81, 3G83, 3G84, 3IKN, 3IKP, 3IKQ, 3IKR, 4E52, 4M17, 4M18
Dynodwyr
Cyfenwau	SFTPD, COLEC7, PSP-D, SFTP4, SP-D, surfactant protein D
Dynodwyr allanol	OMIM: 178635 HomoloGene: 2272 GeneCards: SFTPD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • carbohydrate binding • identical protein binding • lipopolysaccharide binding • monosaccharide binding Cydrannau o'r gell • cytoplasm • collagen • endoplasmic reticulum membrane • clathrin-coated endocytic vesicle • endocytic vesicle • extracellular region • lysosome • extracellular space • multivesicular body • rough endoplasmic reticulum Prosesau biolegol • surfactant homeostasis • positive regulation of phagocytosis • immune system process • receptor-mediated endocytosis • respiratory gaseous exchange by respiratory system • reactive oxygen species metabolic process • GO:0032657 regulation of cytokine production • negative regulation of T cell proliferation • macrophage chemotaxis • defense response to bacterium • regulation of immune response • lung alveolus development • innate immune response • toll-like receptor signaling pathway • induction of bacterial agglutination • regulation of adhesion of symbiont to host epithelial cell • GO:0007571 developmental process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6441	n/a
Ensembl	ENSG00000133661	n/a
UniProt	P35247	n/a
RefSeq (mRNA)	NM_003019	n/a
RefSeq (protein)	NP_003010	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SFTPD yw SFTPD a elwir hefyd yn Surfactant protein D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SFTPD.

• SP-D
• PSP-D
• SFTP4
• COLEC7

Llyfryddiaeth

• "Surfactant Protein D Inhibits Interleukin-12p40 Production by Macrophages Through the SIRPα/ROCK/ERK Signaling Pathway. ". Am J Med Sci. 2017. PMID 28641719.
• "Impact of serum SP-A and SP-D levels on comparison and prognosis of idiopathic pulmonary fibrosis: A systematic review and meta-analysis. ". Medicine (Baltimore). 2017. PMID 28591049.
• "Structure binding relationship of human surfactant protein D and various lipopolysaccharide inner core structures. ". J Struct Biol. 2016. PMID 27350640.
• "Serum Surfactant Protein D is Associated with Atherosclerosis of the Carotid Artery in Patients on Maintenance Hemodialysis. ". Clin Lab. 2016. PMID 27012038.
• "Crystal Structure of a Complex of Surfactant Protein D (SP-D) and Haemophilus influenzae Lipopolysaccharide Reveals Shielding of Core Structures in SP-D-Resistant Strains.". Infect Immun. 2016. PMID 26953329.