SF3A3

SF3A3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DT7
Dynodwyr
Cyfenwau	SF3A3, PRP9, PRPF9, SAP61, SF3a60, splicing factor 3a subunit 3
Dynodwyr allanol	OMIM: 605596 HomoloGene: 4949 GeneCards: SF3A3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • zinc ion binding • GO:0001948, GO:0016582 protein binding • metal ion binding • nucleic acid binding • RNA binding Cydrannau o'r gell • nuclear speck • catalytic step 2 spliceosome • spliceosomal complex • cnewyllyn cell • nucleoplasm • U2 snRNP • U2-type precatalytic spliceosome Prosesau biolegol • RNA splicing, via transesterification reactions • mRNA splicing, via spliceosome • mRNA processing • mRNA 3'-splice site recognition • RNA splicing • U2-type prespliceosome assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10946	n/a
Ensembl	ENSG00000183431	n/a
UniProt	Q12874	n/a
RefSeq (mRNA)	NM_006802 NM_001320830	n/a
RefSeq (protein)	NP_001307759 NP_006793	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SF3A3 yw SF3A3 a elwir hefyd yn Splicing factor 3a subunit 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p34.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SF3A3.

• PRP9
• PRPF9
• SAP61
• SF3a60

Llyfryddiaeth

• "Specific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114. ". Proc Natl Acad Sci U S A. 1994. PMID 8022796.
• "A role for Cajal bodies in the final steps of U2 snRNP biogenesis. ". J Cell Sci. 2004. PMID 15316075.
• "Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo. ". Nucleic Acids Res. 1994. PMID 7816610.
• "Specific inhibition of transcriptional activity of the constitutive androstane receptor (CAR) by the splicing factor SF3a3. ". Biol Chem. 2008. PMID 18713018.
• "Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP.". Structure. 2006. PMID 17098193.