SERPINB2

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SERPINB2
Protein SERPINB2 PDB 1by7.png
Strwythurau
PDBOrthologau:PDBe RCSB
Dynodwyr
CyfenwauSERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2, serpin family B member 2
Dynodwyr allanolOMIM: 173390 MGI: 97609 HomoloGene: 20571 GeneCards: SERPINB2
Patrwm RNA pattern
PBB GE SERPINB2 204614 at fs.png
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002575
NM_001143818

NM_001174170
NM_011111

RefSeq (protein)

NP_001137290
NP_002566

NP_001167641
NP_035241

Lleoliad (UCSC)n/aChr : 107.51 – 107.54 Mb
PubMed search[2][3]
Wicidata
Gweld/Golygu Bod dynolGweld/Golygu Llygoden

Protein sy'n cael ei godio yn y corff dynol gan y genyn SERPINB2 yw SERPINB2 a elwir hefyd yn Plasminogen activator inhibitor 2 a Serpin family B member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q21.33-q22.1.[4]

Cyfystyron[golygu | golygu cod y dudalen]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SERPINB2.

  • PAI
  • PAI2
  • PAI-2
  • PLANH2
  • HsT1201

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs. ". Mol Immunol. 2017. PMID 28578223.
  • "Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation. ". Atherosclerosis. 2016. PMID 27174532.
  • "Variant of PAI-2 gene is associated with coronary artery disease and recurrent coronary event risk in Chinese Han population. ". Lipids Health Dis. 2015. PMID 26573152.
  • "The sGC activator inhibits the proliferation and migration, promotes the apoptosis of human pulmonary arterial smooth muscle cells via the up regulation of plasminogen activator inhibitor-2. ". Exp Cell Res. 2015. PMID 25704756.
  • "SERPINB2 down-regulation contributes to chemoresistance in head and neck cancer.". Mol Carcinog. 2014. PMID 23661500.

Cyfeiriadau[golygu | golygu cod y dudalen]

  1. 1.0 1.1 1.2 GRCm38: Ensembl release 89: ENSMUSG00000062345 - Ensembl, May 2017
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. SERPINB2 - Cronfa NCBI