SEPHS1

SEPHS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3FD5, 3FD6
Dynodwyr
Cyfenwau	SEPHS1, SELD, SPS, SPS1, Selenophosphate synthetase 1
Dynodwyr allanol	OMIM: 600902 HomoloGene: 56558 GeneCards: SEPHS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • selenide, water dikinase activity • GTP binding • GO:0001948, GO:0016582 protein binding • ATP binding • protein homodimerization activity • identical protein binding • protein heterodimerization activity • kinase activity Cydrannau o'r gell • cytoplasm • Cellbilen • nuclear membrane • bilen • cnewyllyn cell Prosesau biolegol • phosphorylation • selenocysteine biosynthetic process • selenium compound metabolic process • tRNA seleno-modification Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	22929	n/a
Ensembl	ENSG00000086475	n/a
UniProt	P49903 Q5T5U7	n/a
RefSeq (mRNA)	NM_001195602 NM_001195604 NM_012247 NM_001375769 NM_001375770	n/a
RefSeq (protein)	NP_001182531 NP_001182533 NP_036379 NP_001362698	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SEPHS1 yw SEPHS1 a elwir hefyd yn Selenide, water dikinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10p13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SEPHS1.

• SPS
• SELD
• SPS1

Llyfryddiaeth

• "p53-Mediated enhancement of radiosensitivity by selenophosphate synthetase 1 overexpression. ". J Cell Physiol. 2006. PMID 16786570.
• "Selenophosphate synthetase genes from lung adenocarcinoma cells: Sps1 for recycling L-selenocysteine and Sps2 for selenite assimilation. ". Proc Natl Acad Sci U S A. 2004. PMID 15534230.
• "Cloning and functional characterization of human selenophosphate synthetase, an essential component of selenoprotein synthesis. ". J Biol Chem. 1995. PMID 7665581.
• "Selenium, selenoprotein genes and Crohn's disease in a case-control population from Auckland, New Zealand. ". Nutrients. 2012. PMID 23112913.
• "Human selenophosphate synthetase 1 has five splice variants with unique interactions, subcellular localizations and expression patterns.". Biochem Biophys Res Commun. 2010. PMID 20471958.