SELL

SELL
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2LGF, 3CFW
Dynodwyr
Cyfenwau	SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L
Dynodwyr allanol	OMIM: 153240 HomoloGene: 539 GeneCards: SELL
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protease binding • heparin binding • GO:0001948, GO:0016582 protein binding • glycosphingolipid binding • cell adhesion molecule binding • carbohydrate binding • calcium ion binding • oligosaccharide binding • metal ion binding Cydrannau o'r gell • integral component of membrane • cell surface • Cellbilen • bilen • external side of plasma membrane • secretory granule membrane • integral component of plasma membrane Prosesau biolegol • response to ATP • cell adhesion • regulation of immune response • neutrophil degranulation • leukocyte migration • calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules • leukocyte tethering or rolling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6402	n/a
Ensembl	ENSG00000188404	n/a
UniProt	P14151	n/a
RefSeq (mRNA)	NM_000655	n/a
RefSeq (protein)	NP_000646	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SELL yw SELL a elwir hefyd yn Selectin L (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SELL.

• TQ1
• LAM1
• LEU8
• LNHR
• LSEL
• CD62L
• LYAM1
• PLNHR
• LECAM1

Llyfryddiaeth

• "Over-expression of a human CD62L ecto-domain and a potential role of RNA pseudoknot structures in recombinant protein expression. ". Protein Expr Purif. 2017. PMID 28842197.
• "Influence of haplotypes, gene expression and soluble levels of L-selectin on the risk of acute coronary syndrome. ". Gene. 2017. PMID 28478085.
• "CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. ". J Clin Invest. 2016. PMID 27183388.
• "Brief Report: L-Selectin (CD62L) Is Downregulated on CD4+ and CD8+ T Lymphocytes of HIV-1-Infected Individuals Naive for ART. ". J Acquir Immune Defic Syndr. 2016. PMID 27003497.
• "L-selectin controls trafficking of chronic lymphocytic leukemia cells in lymph node high endothelial venules in vivo.". Blood. 2015. PMID 26162407.