SELE

SELE
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ESL, 1G1T, 4C16, 4CSY
Dynodwyr
Cyfenwau	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2, selectin E, selectin-e
Dynodwyr allanol	OMIM: 131210 HomoloGene: 389 GeneCards: SELE
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phospholipase binding • oligosaccharide binding • GO:0001948, GO:0016582 protein binding • transmembrane signaling receptor activity • carbohydrate binding • sialic acid binding • metal ion binding Cydrannau o'r gell • integral component of membrane • bilen • cortical cytoskeleton • Cellbilen • perinuclear region of cytoplasm • caveola • membrane raft • clathrin-coated pit • extracellular space • integral component of plasma membrane Prosesau biolegol • leukocyte cell-cell adhesion • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • response to interleukin-1 • positive regulation of receptor internalization • actin filament-based process • leukocyte migration involved in inflammatory response • activation of phospholipase C activity • response to tumor necrosis factor • response to lipopolysaccharide • cell adhesion • regulation of inflammatory response • leukocyte tethering or rolling • inflammatory response • leukocyte migration • calcium-mediated signaling Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6401	n/a
Ensembl	ENSG00000007908	n/a
UniProt	P16581	n/a
RefSeq (mRNA)	NM_000450	n/a
RefSeq (protein)	NP_000441	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SELE yw SELE a elwir hefyd yn Selectin E (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SELE.

• ELAM
• ESEL
• CD62E
• ELAM1
• LECAM2

Llyfryddiaeth

• "The effect of soluble E-selectin on tumor progression and metastasis. ". BMC Cancer. 2016. PMID 27220365.
• "Correlation of E-selectin concentrations with carotid intima-media thickness and cardio-metabolic profile of mixed ancestry South Africans: a cross-sectional study. ". Ann Clin Biochem. 2017. PMID 27141013.
• "E-selectin-mediated rolling facilitates pancreatic cancer cell adhesion to hyaluronic acid. ". FASEB J. 2017. PMID 28765175.
• "Flow-Enhanced Stability of Rolling Adhesion through E-Selectin. ". Biophys J. 2016. PMID 27558713.
• "Evaluation of ELAM-1 expression alteration in endometriosis.". Minerva Ginecol. 2017. PMID 27433816.