SDC4

SDC4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EJP, 1EJQ, 1OBY, 1YBO
Dynodwyr
Cyfenwau	SDC4, SYND4, syndecan 4
Dynodwyr allanol	OMIM: 600017 HomoloGene: 31121 GeneCards: SDC4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • fibronectin binding • GO:0001948, GO:0016582 protein binding • thrombospondin receptor activity • protein kinase C binding • identical protein binding Cydrannau o'r gell • integral component of membrane • bilen • focal adhesion • Cellbilen • integral component of plasma membrane • extracellular region • lysosomal lumen • Golgi lumen • membrane raft • costamere • extracellular exosome • cell surface Prosesau biolegol • glycosaminoglycan metabolic process • ureteric bud development • inner ear receptor cell stereocilium organization • positive regulation of extracellular exosome assembly • wound healing • retinoid metabolic process • neural tube closure • glycosaminoglycan catabolic process • glycosaminoglycan biosynthetic process • positive regulation of focal adhesion assembly • positive regulation of exosomal secretion • regulation of fibroblast migration • positive regulation of stress fiber assembly • positive regulation of protein kinase activity • GO:0072468 signal transduction • negative regulation of T cell proliferation • leukocyte migration • cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6385	n/a
Ensembl	ENSG00000124145	n/a
UniProt	P31431	n/a
RefSeq (mRNA)	NM_002999	n/a
RefSeq (protein)	NP_002990	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SDC4 yw SDC4 a elwir hefyd yn Syndecan 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SDC4.

• SYND4

Llyfryddiaeth

• "Syndecan-4 shedding is involved in the oxidative stress and inflammatory responses in left atrial tissue with valvular atrial fibrillation. ". Int J Clin Exp Pathol. 2015. PMID 26261514.
• "Metabolism and successful aging: Polymorphic variation of syndecan-4 (SDC4) gene associate with longevity and lipid profile in healthy elderly Italian subjects. ". Mech Ageing Dev. 2015. PMID 26254886.
• "Lack of association between serum syndecan-4, myocardial fibrosis and ventricular dysfunction in subjects with chronic Chagas disease. ". PLoS One. 2017. PMID 29232393.
• "Increased syndecan-4 expression in sera and skin of patients with atopic dermatitis. ". Arch Dermatol Res. 2016. PMID 27591995.
• "Syndecan-4 expression is upregulated in endometriosis and contributes to an invasive phenotype.". Fertil Steril. 2016. PMID 27041028.