SCFD1

SCFD1
Dynodwyr
Cyfenwau	SCFD1, C14orf163, RA410, SLY1, SLY1P, STXBP1L2, sec1 family domain containing 1
Dynodwyr allanol	OMIM: 618207 HomoloGene: 5650 GeneCards: SCFD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein N-terminus binding • GO:0001948, GO:0016582 protein binding • syntaxin binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • cytoplasm • cytosol • Golgi apparatus • endoplasmic reticulum membrane • bilen • cis-Golgi network • Cellbilen • Golgi transport complex • Golgi-associated vesicle • Golgi cisterna membrane • Reticwlwm endoplasmig Prosesau biolegol • negative regulation of autophagosome assembly • regulation of ER to Golgi vesicle-mediated transport • response to hypoxia • regulation of protein transport • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • toxin transport • post-Golgi vesicle-mediated transport • vesicle docking involved in exocytosis • COPII vesicle coating • GO:0000767 cell morphogenesis • protein transport • response to toxic substance • vesicle-mediated transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23256	n/a
Ensembl	ENSG00000092108	n/a
UniProt	Q8WVM8	n/a
RefSeq (mRNA)	NM_001257376 NM_001283031 NM_001283032 NM_001283033 NM_016106 NM_182835	n/a
RefSeq (protein)	NP_001244305 NP_001269960 NP_001269961 NP_001269962 NP_057190 NP_878255	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SCFD1 yw SCFD1 a elwir hefyd yn Sec1 family domain containing 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SCFD1.

• SLY1
• RA410
• SLY1P
• STXBP1L2
• C14orf163

Llyfryddiaeth

• "Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins. ". Proc Natl Acad Sci U S A. 2003. PMID 12506202.
• "Cloning of a putative vesicle transport-related protein, RA410, from cultured rat astrocytes and its expression in ischemic rat brain. ". J Biol Chem. 1997. PMID 9195952.
• "RA410/Sly1 suppresses MPP+ and 6-hydroxydopamine-induced cell death in SH-SY5Y cells. ". Neurobiol Dis. 2005. PMID 15649705.
• "Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. ". Nat Genet. 2016. PMID 27455348.
• "rsly1 binding to syntaxin 5 is required for endoplasmic reticulum-to-Golgi transport but does not promote SNARE motif accessibility.". Mol Biol Cell. 2004. PMID 14565970.