SAT1

SAT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2B3U, 2B3V, 2B4B, 2B4D, 2B58, 2B5G, 2F5I, 2FXF, 2G3T, 2JEV
Dynodwyr
Cyfenwau	SAT1, DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1, spermidine/spermine N1-acetyltransferase 1
Dynodwyr allanol	OMIM: 313020 HomoloGene: 37716 GeneCards: SAT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • N-acetyltransferase activity • acyltransferase activity • GO:0001948, GO:0016582 protein binding • spermidine binding • diamine N-acetyltransferase activity • identical protein binding Cydrannau o'r gell • cytoplasm • intracellular anatomical structure • cytosol Prosesau biolegol • polyamine biosynthetic process • regulation of cell population proliferation • angiogenesis • putrescine catabolic process • polyamine catabolic process • polyamine metabolic process • spermidine acetylation • spermine catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6303	n/a
Ensembl	n/a	n/a
UniProt	P21673	n/a
RefSeq (mRNA)	NM_002970	n/a
RefSeq (protein)	NP_002961	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SAT1 yw SAT1 a elwir hefyd yn Spermidine/spermine N1-acetyltransferase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xp22.11.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SAT1.

• SAT
• DC21
• KFSD
• SSAT
• KFSDX
• SSAT-1

Llyfryddiaeth

• "Expression of spermidine/spermine N(1) -acetyl transferase (SSAT) in human prostate tissues is related to prostate cancer progression and metastasis. ". Prostate. 2015. PMID 25893668.
• "Depletion of the polyamines spermidine and spermine by overexpression of spermidine/spermine N¹-acetyltransferase 1 (SAT1) leads to mitochondria-mediated apoptosis in mammalian cells. ". Biochem J. 2015. PMID 25849284.
• "Monoclonal Antibody Against Spermidine/Spermine N1-Acetyltransferase. ". Monoclon Antib Immunodiagn Immunother. 2016. PMID 27328064.
• "Preparation of Antispermidine/Spermine-N1-Acetyltransferase Monoclonal Antibodies. ". Monoclon Antib Immunodiagn Immunother. 2016. PMID 27228136.
• "Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 (SAT1) gene in major depression and suicide.". Neurobiol Dis. 2015. PMID 25959060.