SART3

SART3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DO4, 5JJW, 5JJX, 5CTT, 5CTR, 5JPZ, 5CTQ
Dynodwyr
Cyfenwau	SART3, DSAP1, P100, RP11-13G14, TIP110, p110, p110(nrb), squamous cell carcinoma antigen recognized by T-cells 3, squamous cell carcinoma antigen recognized by T cells 3, spliceosome associated factor 3, U4/U6 recycling protein
Dynodwyr allanol	OMIM: 611684 HomoloGene: 40977 GeneCards: SART3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • U6atac snRNA binding • GO:0031493 histone binding • U4 snRNA binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • ubiquitin-specific protease binding • U6 snRNA binding • RNA binding Cydrannau o'r gell • cytoplasm • Cajal body • nuclear speck • U4/U6 x U5 tri-snRNP complex • nucleoplasm • U4/U6 snRNP • U6atac snRNP • U4atac/U6atac snRNP • cnewyllyn cell • ASAP complex Prosesau biolegol • mRNA splicing, via spliceosome • nucleosome assembly • GO:0033168, GO:0036404, GO:1902360 RNA processing • spliceosomal tri-snRNP complex assembly • homeostasis of number of cells • positive regulation of histone deubiquitination • hematopoietic stem cell proliferation • mRNA processing • spliceosomal snRNP assembly • GO:0000767 cell morphogenesis • RNA splicing • regulation of gene expression • regulation of alternative mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9733	n/a
Ensembl	ENSG00000075856	n/a
UniProt	Q15020	n/a
RefSeq (mRNA)	NM_014706	n/a
RefSeq (protein)	NP_055521	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SART3 yw SART3 a elwir hefyd yn Squamous cell carcinoma antigen recognized by T-cells 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SART3.

• P100
• p110
• DSAP1
• TIP110
• p110(nrb)
• RP11-13G14

Llyfryddiaeth

• "Structural Basis of the Recruitment of Ubiquitin-specific Protease USP15 by Spliceosome Recycling Factor SART3. ". J Biol Chem. 2016. PMID 27255711.
• "Tip110 interacts with YB-1 and regulates each other's function. ". BMC Mol Biol. 2013. PMID 23822148.
• "Tip110 maintains expression of pluripotent factors in and pluripotency of human embryonic stem cells. ". Stem Cells Dev. 2012. PMID 22132941.
• "3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins. ". RNA. 2008. PMID 18567812.
• "A mutation in SART3 gene in a Chinese pedigree with disseminated superficial actinic porokeratosis.". Br J Dermatol. 2005. PMID 15840095.