SAR1B

SAR1B
Dynodwyr
Cyfenwau	SAR1B, ANDD, CMRD, GTBPB, SARA2, secretion associated Ras related GTPase 1B
Dynodwyr allanol	OMIM: 607690 HomoloGene: 90905 GeneCards: SAR1B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • metal ion binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytosol • Golgi apparatus • endoplasmic reticulum membrane • bilen • intracellular anatomical structure • Golgi cisterna membrane • Reticwlwm endoplasmig • ER to Golgi transport vesicle membrane • COPII vesicle coat • endoplasmic reticulum exit site Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • antigen processing and presentation of peptide antigen via MHC class I • endoplasmic reticulum to Golgi vesicle-mediated transport • COPII vesicle coating • protein transport • intracellular protein transport • vesicle-mediated transport • regulation of COPII vesicle coating • vesicle organization • membrane organization • positive regulation of protein exit from endoplasmic reticulum Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51128	n/a
Ensembl	ENSG00000152700	n/a
UniProt	Q9Y6B6	n/a
RefSeq (mRNA)	NM_016103 NM_001033503	n/a
RefSeq (protein)	NP_001028675 NP_057187	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SAR1B yw SAR1B a elwir hefyd yn Secretion associated Ras related GTPase 1B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SAR1B.

• ANDD
• CMRD
• GTBPB
• SARA2

Llyfryddiaeth

• "Anderson's disease (chylomicron retention disease): a new mutation in the SARA2 gene associated with muscular and cardiac abnormalities. ". Clin Genet. 2008. PMID 18786134.
• "Anderson or chylomicron retention disease: molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein. ". Mol Genet Metab. 2008. PMID 17945526.
• "Understanding Chylomicron Retention Disease Through Sar1b Gtpase Gene Disruption: Insight From Cell Culture. ". Arterioscler Thromb Vasc Biol. 2017. PMID 28982670.
• "New Insights In Intestinal Sar1B GTPase Regulation and Role in Cholesterol Homeostasis. ". J Cell Biochem. 2015. PMID 25826777.
• "Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 gene.". Metabolism. 2010. PMID 19846172.