S100A4

S100A4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1M31, 2LNK, 2MRD, 2Q91, 3C1V, 3CGA, 3KO0, 3M0W, 3ZWH, 4CFQ, 4CFR, 4ETO, 4HSZ
Dynodwyr
Cyfenwau	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, S100 calcium binding protein A4
Dynodwyr allanol	OMIM: 114210 HomoloGene: 7924 GeneCards: S100A4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • actin binding • GO:0001948, GO:0016582 protein binding • calcium-dependent protein binding • metal ion binding • RAGE receptor binding • RNA binding • transition metal ion binding • identical protein binding Cydrannau o'r gell • perinuclear region of cytoplasm • neuron projection • extracellular exosome • cnewyllyn cell • extracellular space • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • positive regulation of I-kappaB kinase/NF-kappaB signaling • epithelial to mesenchymal transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6275	n/a
Ensembl	ENSG00000196154	n/a
UniProt	P26447	n/a
RefSeq (mRNA)	NM_019554 NM_002961	n/a
RefSeq (protein)	NP_002952 NP_062427	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn S100A4 yw S100A4 a elwir hefyd yn S100 calcium binding protein A4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn S100A4.

• 42A
• 18A2
• CAPL
• FSP1
• MTS1
• P9KA
• PEL98

Llyfryddiaeth

• "S100A4 accelerates the proliferation and invasion of endometrioid carcinoma and is associated with the "MELF" pattern. ". Cancer Sci. 2016. PMID 27348205.
• "Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma. ". Cancer Res. 2016. PMID 27328733.
• "Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer. ". Breast Cancer Res Treat. 2017. PMID 28058579.
• "S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer. ". Cancer Res. 2017. PMID 27927689.
• "Knockdown of S100A4 blocks growth and metastasis of anaplastic thyroid cancer cells in vitro and in vivo.". Cancer Biomark. 2016. PMID 27802204.