RTN4

RTN4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2G31, 2JV5
Dynodwyr
Cyfenwau	RTN4, ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C, Reticulon 4
Dynodwyr allanol	OMIM: 604475 HomoloGene: 10743 GeneCards: RTN4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • RNA binding • cadherin binding • ubiquitin protein ligase binding Cydrannau o'r gell • integral component of membrane • cell projection • nuclear envelope • bilen • integral component of endoplasmic reticulum membrane • intracellular anatomical structure • Reticwlwm endoplasmig • endoplasmic reticulum membrane • Cellbilen • extracellular exosome • GO:0097483, GO:0097481 postsynaptic density • endoplasmic reticulum tubular network • neuronal cell body • endoplasmic reticulum tubular network membrane • cell junction Prosesau biolegol • nuclear pore complex assembly • regulation of apoptotic process • cerebral cortex radial glia-guided migration • regulation of branching morphogenesis of a nerve • cardiac epithelial to mesenchymal transition • negative regulation of axon extension • GO:0097285 apoptotic process • negative regulation of axonogenesis • nervous system development • regulation of nervous system development • endoplasmic reticulum tubular network formation • endoplasmic reticulum tubular network organization • regulation of cell migration • negative regulation of cell growth • axonal fasciculation • positive regulation of epithelial cell migration • positive regulation of mammary gland epithelial cell proliferation • protein stabilization • positive regulation of protein kinase B signaling • positive regulation of protein localization to endoplasmic reticulum • positive regulation of ERBB3 signaling pathway • endoplasmic reticulum tubular network membrane organization • blastocyst formation • positive regulation of toll-like receptor 9 signaling pathway • protein localization to lysosome • cellular sphingolipid homeostasis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	57142	n/a
Ensembl	ENSG00000115310	n/a
UniProt	Q9NQC3	n/a
RefSeq (mRNA)	NM_007008 NM_020532 NM_153828 NM_207520 NM_207521 NM_001321859 NM_001321860 NM_001321861 NM_001321862 NM_001321863 NM_001321904	n/a
RefSeq (protein)	NP_001308788 NP_001308789 NP_001308790 NP_001308791 NP_001308792 NP_001308833 NP_008939 NP_065393 NP_722550 NP_997403 NP_997404	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RTN4 yw RTN4 a elwir hefyd yn Reticulon 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p16.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RTN4.

• ASY
• NSP
• NOGO
• RTN-X
• NSP-CL
• RTN4-A
• RTN4-C
• RTN4-B1
• RTN4-B2
• NI220/250
• Nbla00271
• Nbla10545

Llyfryddiaeth

• "RTN4 3'-UTR insertion/deletion polymorphism and susceptibility to non-small cell lung cancer in Chinese Han population. ". Asian Pac J Cancer Prev. 2014. PMID 25040983.
• "Nogo-C contributes to HCC tumorigenesis via suppressing cell growth and its interactome analysis with comparative proteomics research. ". Int J Clin Exp Pathol. 2014. PMID 24966913.
• "Prognostic Significance of NOGO-A/B and NOGO-B Receptor Expression in Malignant Melanoma - A Preliminary Study. ". Anticancer Res. 2016. PMID 27354599.
• "Down-Regulation of Nogo-B Expression as a Newly Identified Feature of Intrahepatic Cholangiocarcinoma. ". Tohoku J Exp Med. 2016. PMID 26656426.
• "Knockdown of reticulon 4C by lentivirus inhibits human colorectal cancer cell growth.". Mol Med Rep. 2015. PMID 25847052.