RRAD

RRAD
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DPX, 2GJS, 3Q72, 3Q7P, 3Q7Q
Dynodwyr
Cyfenwau	RRAD, RAD, RAD1, REM3, Ras related glycolysis inhibitor and calcium channel regulator
Dynodwyr allanol	OMIM: 179503 HomoloGene: 3071 GeneCards: RRAD
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • calmodulin binding • GO:0006184 GTPase activity • calcium channel regulator activity Cydrannau o'r gell • Cellbilen • bilen • intracellular anatomical structure Prosesau biolegol • GO:0072468 signal transduction • small GTPase mediated signal transduction • regulation of high voltage-gated calcium channel activity • negative regulation of high voltage-gated calcium channel activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6236	n/a
Ensembl	ENSG00000166592	n/a
UniProt	P55042	n/a
RefSeq (mRNA)	NM_004165 NM_001128850	n/a
RefSeq (protein)	NP_001122322 NP_004156	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RRAD yw RRAD a elwir hefyd yn GTP-binding protein RAD a RRAD, Ras related glycolysis inhibitor and calcium channel regulator (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q22.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RRAD.

• RAD
• RAD1
• REM3

Llyfryddiaeth

• "Rad knockdown induces mitochondrial apoptosis in bortezomib resistant leukemia and lymphoma cells. ". Leuk Res. 2012. PMID 22658652.
• "Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. ". Cancer Lett. 2012. PMID 22487779.
• "RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma. ". Tumour Biol. 2016. PMID 26546438.
• "Rad GTPase inhibits the NFκB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation. ". Cell Signal. 2014. PMID 24632303.
• "Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer.". Anticancer Res. 2013. PMID 24222170.