RP2

RP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BX6, 3BH6, 3BH7
Dynodwyr
Cyfenwau	RP2, DELXp11.3, NM23-H10, NME10, TBCCD2, Xretinitis pigmentosa 2 (X-linked recessive), ARL3 GTPase activating protein, RP2 activator of ARL3 GTPase
Dynodwyr allanol	OMIM: 300757 HomoloGene: 5042 GeneCards: RP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • unfolded protein binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • magnesium ion binding Cydrannau o'r gell • cytoplasm • ciliary basal body • Golgi apparatus • cell projection • bilen • Cellbilen • periciliary membrane compartment • centriole • extracellular exosome • GO:0016023 cytoplasmic vesicle • nucleoplasm • cilium • nuclear body Prosesau biolegol • post-chaperonin tubulin folding pathway • post-Golgi vesicle-mediated transport • protein folding • protein transport • golwg • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • GO:0015915 transport • GO:0000767 cell morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6102	n/a
Ensembl	ENSG00000102218	n/a
UniProt	O75695	n/a
RefSeq (mRNA)	NM_006915	n/a
RefSeq (protein)	NP_008846	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RP2 yw RP2 a elwir hefyd yn RP2, ARL3 GTPase activating protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom X dynol, band Xp11.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RP2.

• XRP2
• NME10
• TBCCD2
• NM23-H10
• DELXp11.3

Llyfryddiaeth

• "Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells. ". Hum Mol Genet. 2015. PMID 25292197.
• "5meCpG epigenetic marks neighboring a primate-conserved core promoter short tandem repeat indicate X-chromosome inactivation. ". PLoS One. 2014. PMID 25078280.
• "Single-Exome sequencing identified a novel RP2 mutation in a child with X-linked retinitis pigmentosa. ". Can J Ophthalmol. 2016. PMID 27769321.
• "Pattern dystrophy in a female carrier of RP2 mutation. ". Ophthalmic Genet. 2016. PMID 26885761.
• "Lipid Selectivity, Orientation, and Extent of Membrane Binding of Nonacylated RP2.". Biochemistry. 2015. PMID 25844643.