RORB

RORB
Dynodwyr
Cyfenwau	RORB, NR1F2, ROR-BETA, RZR-BETA, RZRB, bA133M9.1, RAR-related orphan receptor beta, RAR related orphan receptor B, EIG15
Dynodwyr allanol	OMIM: 601972 HomoloGene: 38250 GeneCards: RORB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sequence-specific DNA binding • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • zinc ion binding • transcription factor binding • metal ion binding • steroid hormone receptor activity • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • GO:0001948, GO:0016582 protein binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • melatonin receptor activity Cydrannau o'r gell • nucleoplasm • cnewyllyn cell Prosesau biolegol • cellular response to retinoic acid • GO:0009373 regulation of transcription, DNA-templated • response to stimulus • proses rythmig • retinal cone cell development • negative regulation of osteoblast differentiation • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • multicellular organism development • regulation of circadian rhythm • retinal rod cell development • eye photoreceptor cell development • transcription initiation from RNA polymerase II promoter • GO:0045996 negative regulation of transcription, DNA-templated • golwg • steroid hormone mediated signaling pathway • intracellular receptor signaling pathway • amacrine cell differentiation • retina development in camera-type eye • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • G protein-coupled receptor signaling pathway • transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6096	n/a
Ensembl	ENSG00000198963	n/a
UniProt	Q92753 Q58EY0	n/a
RefSeq (mRNA)	NM_006914 NM_001365023	n/a
RefSeq (protein)	NP_008845 NP_001351952	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RORB yw RORB a elwir hefyd yn RAR related orphan receptor B a Nuclear receptor ROR-beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q21.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RORB.

• RZRB
• NR1F2
• ROR-BETA
• RZR-BETA
• bA133M9.1

Llyfryddiaeth

• "Differential transcription of the orphan receptor RORbeta in nuclear extracts derived from Neuro2A and HeLa cells. ". Nucleic Acids Res. 2001. PMID 11504880.
• "Functional analysis of retinoid Z receptor beta, a brain-specific nuclear orphan receptor. ". Proc Natl Acad Sci U S A. 1996. PMID 8816759.
• "Loss of function of the retinoid-related nuclear receptor (RORB) gene and epilepsy. ". Eur J Hum Genet. 2016. PMID 27352968.
• "Retinoic acid-related orphan receptor RORβ, circadian rhythm abnormalities and tumorigenesis (Review). ". Int J Mol Med. 2015. PMID 25816151.
• "Rhythmic expression of ROR beta mRNA in the mice suprachiasmatic nucleus.". Neurosci Lett. 2002. PMID 11849752.