RNMT

RNMT
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3BGV, 3EPP, 5E9J, 5E9W, 5E8J
Dynodwyr
Cyfenwau	RNMT, MET, RG7MT1, hCMT1c, CMT1, CMT1c, cm1p, hCMT1, hMet, MRNA-methyltransferase, RNA guanine-7 methyltransferase, N7-MTase
Dynodwyr allanol	OMIM: 603514 HomoloGene: 2816 GeneCards: RNMT
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0102674, GO:0102675 methyltransferase activity • transferase activity • mRNA (guanine-N7-)-methyltransferase activity • GO:0001948, GO:0016582 protein binding • RNA binding Cydrannau o'r gell • mRNA cap binding complex • receptor complex • cnewyllyn cell • nucleoplasm • fibrillar center • mRNA cap methyltransferase complex Prosesau biolegol • mRNA processing • methylation • transcription by RNA polymerase II • RNA 5'-cap (guanine-N7)-methylation • cellular response to leukemia inhibitory factor • 7-methylguanosine mRNA capping Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8731	n/a
Ensembl	ENSG00000101654	n/a
UniProt	O43148	n/a
RefSeq (mRNA)	NM_001308263 NM_003799 NM_001378132 NM_001378134 NM_001378135	n/a
RefSeq (protein)	NP_001295192 NP_003790 NP_001365061 NP_001365063 NP_001365064	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNMT yw RNMT a elwir hefyd yn RNA guanine-7 methyltransferase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18p11.21.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RNMT.

• MET
• Met
• CMT1
• cm1p
• hMet
• CMT1c
• hCMT1
• RG7MT1

Llyfryddiaeth

• "The Candida albicans gene for mRNA 5-cap methyltransferase: identification of additional residues essential for catalysis. ". Microbiology. 1999. PMID 10589710.
• "Post-transcriptional modifications of mRNA. Purification and characterization of cap I and cap II RNA (nucleoside-2'-)-methyltransferases from HeLa cells. ". J Biol Chem. 1981. PMID 7275966.
• "RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs. ". Nucleic Acids Res. 2017. PMID 28981715.
• "Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites. ". Biochem J. 2013. PMID 23863084.
• "Human mRNA cap methyltransferase: alternative nuclear localization signal motifs ensure nuclear localization required for viability.". Mol Cell Biol. 2005. PMID 15767670.