RNH1

RNH1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Z7X, 1A4Y, 2BEX, 2Q4G
Dynodwyr
Cyfenwau	RNH1, RAI, RNH, ribonuclease/angiogenin inhibitor 1
Dynodwyr allanol	OMIM: 173320 HomoloGene: 2204 GeneCards: RNH1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ribonuclease inhibitor activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • angiogenin-PRI complex • extracellular exosome • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • regulation of angiogenesis • mRNA catabolic process • GO:0048553 negative regulation of catalytic activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6050	n/a
Ensembl	ENSG00000276230 ENSG00000023191	n/a
UniProt	P13489	n/a
RefSeq (mRNA)	NM_002939 NM_203383 NM_203384 NM_203385 NM_203386 NM_203387 NM_203388 NM_203389	n/a
RefSeq (protein)	NP_002930 NP_976317 NP_976318 NP_976319 NP_976320 NP_976321 NP_976322 NP_976323	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNH1 yw RNH1 a elwir hefyd yn Ribonuclease/angiogenin inhibitor 1 a Ribonuclease inhibitor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p15.5.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RNH1.

• RAI
• RNH

Llyfryddiaeth

• "Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials. ". Mol Cell Biochem. 2011. PMID 21125316.
• "Interaction of onconase with the human ribonuclease inhibitor protein. ". Biochem Biophys Res Commun. 2008. PMID 18930025.
• "Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway. ". Exp Mol Pathol. 2014. PMID 24768914.
• "RNH1 regulation of reactive oxygen species contributes to histone deacetylase inhibitor resistance in gastric cancer cells. ". Oncogene. 2014. PMID 23584480.
• "The ribonuclease/angiogenin inhibitor is also present in mitochondria and nuclei.". FEBS Lett. 2011. PMID 21276451.