RNGTT

RNGTT
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2C46, 3S24
Dynodwyr
Cyfenwau	RNGTT, CAP1A, HCE, HCE1, hCAP, RNA guanylyltransferase and 5'-phosphatase
Dynodwyr allanol	OMIM: 603512 HomoloGene: 37851 GeneCards: RNGTT
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein tyrosine/serine/threonine phosphatase activity • GO:0098519, GO:0098518 phosphatase activity • protein tyrosine phosphatase activity • polynucleotide 5'-phosphatase activity • RNA guanylyltransferase activity • triphosphatase activity • nucleotidyltransferase activity • mRNA guanylyltransferase activity • catalytic activity • hydrolase activity • nucleotide binding • GTP binding • transferase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • nucleoplasm Prosesau biolegol • mRNA processing • GO:0033168, GO:0036404, GO:1902360 RNA processing • GO:0016576 protein dephosphorylation • transcription by RNA polymerase II • GO:0098501, GO:0098502, GO:0006286 dephosphorylation • 7-methylguanosine mRNA capping • metabolaeth • peptidyl-tyrosine dephosphorylation • polynucleotide 5' dephosphorylation • GO:0022415 viral process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8732	n/a
Ensembl	ENSG00000111880	n/a
UniProt	O60942	n/a
RefSeq (mRNA)	NM_001286426 NM_001286428 NM_003800	n/a
RefSeq (protein)	NP_001273355 NP_001273357 NP_003791	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNGTT yw RNGTT a elwir hefyd yn RNA guanylyltransferase and 5'-phosphatase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q15.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RNGTT.

• HCE
• HCE1
• hCAP
• CAP1A

Llyfryddiaeth

• "Transcription elongation factor hSPT5 stimulates mRNA capping. ". Genes Dev. 1999. PMID 10421630.
• "Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively. ". Genomics. 1998. PMID 9828141.
• "The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme. ". PLoS One. 2013. PMID 23349942.
• "Structure of the guanylyltransferase domain of human mRNA capping enzyme. ". Proc Natl Acad Sci U S A. 2011. PMID 21636784.
• "Tat stimulates cotranscriptional capping of HIV mRNA.". Mol Cell. 2002. PMID 12408826.