RND3

RND3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1M7B, 2V55, 4BG6
Dynodwyr
Cyfenwau	RND3, ARHE, Rho8, RhoE, memB, Rnd3, Rho family GTPase 3
Dynodwyr allanol	OMIM: 602924 HomoloGene: 21074 GeneCards: RND3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • protein kinase binding Cydrannau o'r gell • Golgi membrane • Golgi apparatus • extracellular exosome • bilen • focal adhesion • intracellular anatomical structure • cytoplasm • Cellbilen • cell cortex • cell division site • intracellular membrane-bounded organelle Prosesau biolegol • small GTPase mediated signal transduction • cell adhesion • actin cytoskeleton organization • actin filament organization • Rho protein signal transduction • regulation of cell shape • regulation of cell migration • establishment or maintenance of actin cytoskeleton polarity • regulation of actin cytoskeleton organization • actin filament bundle assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	390	n/a
Ensembl	ENSG00000115963	n/a
UniProt	P61587	n/a
RefSeq (mRNA)	NM_005168 NM_001254738	n/a
RefSeq (protein)	NP_001241667 NP_005159	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RND3 yw RND3 a elwir hefyd yn Rho family GTPase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RND3.

• ARHE
• Rho8
• RhoE
• memB

Llyfryddiaeth

• "The Rho GTPase RhoE exerts tumor-suppressing effects in human esophageal squamous cell carcinoma via negatively regulating epidermal growth factor receptor. ". J Cancer Res Ther. 2016. PMID 27721256.
• "Chaperone-mediated autophagy regulates proliferation by targeting RND3 in gastric cancer. ". Autophagy. 2016. PMID 26761524.
• "Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer. ". PLoS Genet. 2015. PMID 26132659.
• "Rnd3 regulates lung cancer cell proliferation through notch signaling. ". PLoS One. 2014. PMID 25372032.
• "Small GTPase RhoE/Rnd3 is a critical regulator of Notch1 signaling.". Cancer Res. 2014. PMID 24525741.