RND1

RND1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CLS, 2REX, 3Q3J
Dynodwyr
Cyfenwau	RND1, ARHS, RHO6, RHOS, Rnd1, Rho family GTPase 1
Dynodwyr allanol	OMIM: 609038 HomoloGene: 8706 GeneCards: RND1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • signaling receptor binding • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • protein kinase binding Cydrannau o'r gell • cytoplasm • adherens junction • cytosol • Cytosgerbwd • bilen • Cellbilen • actin cytoskeleton • intracellular membrane-bounded organelle • intracellular anatomical structure • cell cortex • cell division site Prosesau biolegol • neuron remodeling • small GTPase mediated signal transduction • negative regulation of cell adhesion • actin filament organization • Rho protein signal transduction • regulation of cell shape • regulation of cell migration • establishment or maintenance of actin cytoskeleton polarity • regulation of actin cytoskeleton organization • actin filament bundle assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27289	n/a
Ensembl	ENSG00000172602	n/a
UniProt	Q92730	n/a
RefSeq (mRNA)	NM_014470	n/a
RefSeq (protein)	NP_055285	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RND1 yw RND1 a elwir hefyd yn Rho-related GTP-binding protein Rho6 a Rho family GTPase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RND1.

• ARHS
• RHO6
• RHOS

Llyfryddiaeth

• "Structural basis of Rnd1 binding to plexin Rho GTPase binding domains (RBDs). ". J Biol Chem. 2011. PMID 21610070.
• "Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells. ". Biochem Biophys Res Commun. 2000. PMID 11095956.
• "RND1 is up-regulated in esophageal squamous cell carcinoma and promotes the growth and migration of cancer cells. ". Tumour Biol. 2016. PMID 26250459.
• "The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. ". Nat Cell Biol. 2015. PMID 25531777.
• "Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion.". Biochem Soc Trans. 2016. PMID 27913679.