RNASE2

RNASE2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1GQV, 1HI2, 1HI3, 1HI4, 1HI5, 1K2A, 2BEX, 2BZZ, 2C01, 2C02, 2C05, 5E13
Dynodwyr
Cyfenwau	RNASE2, EDN, RAF3, RNS2, ribonuclease A family member 2
Dynodwyr allanol	OMIM: 131410 HomoloGene: 121614 GeneCards: RNASE2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nuclease activity • endonuclease activity • hydrolase activity • ribonuclease A activity • nucleic acid binding • lipopolysaccharide binding • ribonuclease activity • lyase activity Cydrannau o'r gell • extracellular region • lysosome • extracellular exosome • azurophil granule lumen Prosesau biolegol • chemotaxis • RNA catabolic process • RNA phosphodiester bond hydrolysis, endonucleolytic • positive regulation of protein targeting to mitochondrion • neutrophil degranulation • induction of bacterial agglutination • GO:0051636 defense response to Gram-negative bacterium • GO:0051637 defense response to Gram-positive bacterium • RNA phosphodiester bond hydrolysis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6036	n/a
Ensembl	ENSG00000169385	n/a
UniProt	P10153	n/a
RefSeq (mRNA)	NM_002934	n/a
RefSeq (protein)	NP_002925	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RNASE2 yw RNASE2 a elwir hefyd yn Ribonuclease A family member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q11.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RNASE2.

• EDN
• RAF3
• RNS2

Llyfryddiaeth

• "Eosinophil-derived neurotoxin as a biomarker for disease severity and relapse in recalcitrant atopic dermatitis. ". Ann Allergy Asthma Immunol. 2017. PMID 28866306.
• "Serum eosinophil-derived neurotoxin: correlation with persistent airflow limitation in adults with house-dust mite allergic asthma. ". Allergy Asthma Proc. 2015. PMID 26534742.
• "Elevation of fecal eosinophil-derived neurotoxin in infants with food protein-induced enterocolitis syndrome. ". Pediatr Allergy Immunol. 2014. PMID 24890227.
• "Eosinophil-derived neurotoxin is elevated in patients with amyotrophic lateral sclerosis. ". Mediators Inflamm. 2013. PMID 23533305.
• "An extragranular compartment of blood eosinophils contains eosinophil protein X/eosinophil-derived neurotoxin (EPX/EDN).". Inflammation. 2013. PMID 23053729.