RHOQ

RHOQ
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ATX
Dynodwyr
Cyfenwau	RHOQ, ARHQ, HEL-S-42, RASL7A, TC10, TC10A, ras homolog family member Q
Dynodwyr allanol	OMIM: 605857 HomoloGene: 22704 GeneCards: RHOQ
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GBD domain binding • profilin binding • nucleotide binding • GTP binding • GO:0006184 GTPase activity • protein kinase binding Cydrannau o'r gell • cytoplasm • cytosol • bilen • Cellbilen • Microffilament • membrane raft • Golgi-associated vesicle membrane • extracellular exosome • intracellular anatomical structure • cell cortex • cell projection Prosesau biolegol • positive regulation of glucose import • GO:1901047 insulin receptor signaling pathway • regulation of actin cytoskeleton organization • regulation of cell shape • cellular response to insulin stimulus • regulation of small GTPase mediated signal transduction • GO:0033109 cortical actin cytoskeleton organization • positive regulation of filopodium assembly • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GTP metabolic process • small GTPase mediated signal transduction • negative regulation of protein localization to plasma membrane • endocytosis • actin filament organization • establishment or maintenance of cell polarity • Rho protein signal transduction • cell projection assembly • actin cytoskeleton organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23433	n/a
Ensembl	ENSG00000119729	n/a
UniProt	P17081	n/a
RefSeq (mRNA)	NM_012249	n/a
RefSeq (protein)	NP_036381	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RHOQ yw RHOQ a elwir hefyd yn Rho-related GTP-binding protein RhoQ (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p21.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RHOQ.

• ARHQ
• TC10
• TC10A
• RASL7A
• HEL-S-42

Llyfryddiaeth

• "TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin. ". J Cell Sci. 2009. PMID 19258391.
• "The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes. ". Mol Cell Biol. 2003. PMID 12529401.
• "RNA editing in RHOQ promotes invasion potential in colorectal cancer. ". J Exp Med. 2014. PMID 24663214.
• "GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion. ". Dev Cell. 2006. PMID 16950130.
• "Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin.". Mol Biol Cell. 2003. PMID 12972548.