RHOC

RHOC
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Z2C, 2GCN, 2GCO, 2GCP
Dynodwyr
Cyfenwau	RHOC, ARH9, ARHC, H9, RHOH9, RhoC, ras homolog family member C
Dynodwyr allanol	OMIM: 165380 HomoloGene: 90945 GeneCards: RHOC
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GTP binding • GO:0001948, GO:0016582 protein binding • signal transducer activity • GO:0006184 GTPase activity Cydrannau o'r gell • cytosol • Cellbilen • cleavage furrow • extracellular exosome • bilen • cnewyllyn cell • intracellular anatomical structure • stereocilium Prosesau biolegol • positive regulation of I-kappaB kinase/NF-kappaB signaling • skeletal muscle satellite cell migration • regulation of small GTPase mediated signal transduction • apical junction assembly • wound healing, spreading of cells • positive regulation of lipase activity • small GTPase mediated signal transduction • positive regulation of protein homooligomerization • mitotic cytokinesis • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	389	n/a
Ensembl	ENSG00000155366	n/a
UniProt	P08134 Q5JR06	n/a
RefSeq (mRNA)	NM_175744 NM_001042678 NM_001042679	n/a
RefSeq (protein)	NP_001036143 NP_001036144 NP_786886	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RHOC yw RHOC a elwir hefyd yn Rho-related GTP-binding protein RhoC a Ras homolog family member C (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RHOC.

• H9
• ARH9
• ARHC
• RHOH9

Llyfryddiaeth

• "Effects and mechanism of RhoC downregulation in suppressing ovarian cancer stem cell proliferation, drug resistance, invasion and metastasis. ". Oncol Rep. 2016. PMID 27748937.
• "RhoC GTPase Is a Potent Regulator of Glutamine Metabolism and N-Acetylaspartate Production in Inflammatory Breast Cancer Cells. ". J Biol Chem. 2016. PMID 27129239.
• "Smart Nanoparticles Enhance the Cytoplasmic Delivery of Anti-RhoC Silencing RNA and Inhibit the Migration and Invasion of Aggressive Breast Cancer Cells. ". Mol Pharm. 2015. PMID 26020100.
• "RhoC mediates epidermal growth factor-stimulated migration and invasion in head and neck squamous cell carcinoma. ". Neoplasia. 2015. PMID 25622907.
• "RhoC upregulation is correlated with reduced E-cadherin in human breast cancer specimens after chemotherapy and in human breast cancer MCF-7 cells.". Horm Cancer. 2014. PMID 25123151.