RGS6

RGS6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ES0
Dynodwyr
Cyfenwau	RGS6, GAP, regulator of G-protein signaling 6, regulator of G protein signaling 6, HA117, S914
Dynodwyr allanol	OMIM: 603894 HomoloGene: 68385 GeneCards: RGS6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0006184 GTPase activity Cydrannau o'r gell • cytosol • Cellbilen • bilen • cnewyllyn cell • extrinsic component of membrane • cytoplasm • intracellular anatomical structure Prosesau biolegol • G protein-coupled receptor signaling pathway • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • negative regulation of signal transduction • GO:0007243 intracellular signal transduction • regulation of G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9628	n/a
Ensembl	ENSG00000182732	n/a
UniProt	P49758	n/a
RefSeq (mRNA)	NM_001204416 NM_001204417 NM_001204418 NM_001204419 NM_001204420 NM_001204421 NM_001204422 NM_001204423 NM_001204424 NM_004296	n/a
RefSeq (protein)	NP_001191345 NP_001191346 NP_001191347 NP_001191348 NP_001191349 NP_001191350 NP_001191351 NP_001191352 NP_001191353 NP_004287 NP_001357199 NP_001357200 NP_001357201 NP_001357202 NP_001357203 NP_001357204 NP_001357205 NP_001357206 NP_001357207 NP_001357208 NP_001357209 NP_001357210 NP_001357211 NP_001357212 NP_001357213 NP_001357215 NP_001357216 NP_001357217 NP_001357218 NP_001357219 NP_001357220 NP_001357221 NP_001357222 NP_001357223	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS6 yw RGS6 a elwir hefyd yn Regulator of G protein signaling 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q24.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS6.

• GAP
• S914
• HA117

Llyfryddiaeth

• "RGS6: a novel gene associated with congenital cataract, mental retardation, and microcephaly in a Tunisian family. ". Invest Ophthalmol Vis Sci. 2014. PMID 25525169.
• "Decreased RGS6 expression is associated with poor prognosis in pancreatic cancer patients. ". Int J Clin Exp Pathol. 2014. PMID 25120791.
• "HA117 endows HL60 cells with a stem-like signature by inhibiting the degradation of DNMT1 via its ability to down-regulate expression of the GGL domain of RGS6. ". PLoS One. 2017. PMID 28665981.
• "Interaction between the RGS6 gene and psychosocial stress on obesity-related traits. ". Endocr J. 2017. PMID 28090039.
• "Prognostic value of regulator of G-protein signaling 6 in colorectal cancer.". Biomed Pharmacother. 2015. PMID 26653562.