RGS4

RGS4
Dynodwyr
Cyfenwau	RGS4, Rgs4, AA004315, AA597169, ESTM48, ESTM50, RGP4, SCZD9, regulator of G-protein signaling 4, regulator of G protein signaling 4
Dynodwyr allanol	OMIM: 602516 HomoloGene: 4100 GeneCards: RGS4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G-protein alpha-subunit binding • calmodulin binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • cytosol • Cellbilen • bilen • cnewyllyn cell • GO:0009327 protein-containing complex Prosesau biolegol • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • negative regulation of signal transduction • negative regulation of G protein-coupled receptor signaling pathway • regulation of G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • response to amphetamine • brain development • positive regulation of heart rate • adwaith i gocên • response to morphine • response to ethanol • regulation of calcium ion transport • negative regulation of dopamine receptor signaling pathway • negative regulation of cell growth involved in cardiac muscle cell development • regulation of actin filament organization • negative regulation of glycine import across plasma membrane • regulation of potassium ion transmembrane transport • negative regulation of potassium ion transmembrane transport • dorsal root ganglion development • positive regulation of excitatory postsynaptic potential Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5999	n/a
Ensembl	ENSG00000117152	n/a
UniProt	P49798	n/a
RefSeq (mRNA)	NM_001102445 NM_001113380 NM_001113381 NM_005613	n/a
RefSeq (protein)	NP_001095915 NP_001106851 NP_001106852 NP_005604 NP_005604.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS4 yw RGS4 a elwir hefyd yn Regulator of G-protein signalling 4, isoform CRA_a , Regulator of G-protein-signaling 4 a Regulator of G protein signaling 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS4.

• RGP4
• SCZD9

Llyfryddiaeth

• "An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. ". PLoS One. 2012. PMID 22253691.
• "Lack of association between the regulator of G-protein signaling 4 (RGS4) rs951436 polymorphism and schizophrenia. ". Psychiatr Genet. 2012. PMID 22157635.
• "Association between RGS4 variants and psychotic-like experiences in nonclinical individuals. ". Eur Arch Psychiatry Clin Neurosci. 2017. PMID 26910404.
• "Regulator of G-protein signaling 4: A novel tumor suppressor with prognostic significance in non-small cell lung cancer. ". Biochem Biophys Res Commun. 2016. PMID 26640232.
• "Amino-terminal cysteine residues differentially influence RGS4 protein plasma membrane targeting, intracellular trafficking, and function.". J Biol Chem. 2012. PMID 22753418.