RGS19

RGS19
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CMZ
Dynodwyr
Cyfenwau	RGS19, GAIP, RGSGAIP, regulator of G-protein signaling 19, regulator of G protein signaling 19
Dynodwyr allanol	OMIM: 605071 HomoloGene: 23320 GeneCards: RGS19
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0001948, GO:0016582 protein binding • G-protein alpha-subunit binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • Golgi apparatus • bilen • brush border • heterotrimeric G-protein complex • membrane raft • clathrin-coated vesicle • GO:0016023 cytoplasmic vesicle • Cellbilen Prosesau biolegol • G protein-coupled receptor signaling pathway • small GTPase mediated signal transduction • autophagy • negative regulation of signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • response to ethanol Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10287	n/a
Ensembl	ENSG00000171700	n/a
UniProt	P49795	n/a
RefSeq (mRNA)	NM_001039467 NM_005873	n/a
RefSeq (protein)	NP_001034556 NP_005864	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS19 yw RGS19 a elwir hefyd yn Regulator of G protein signaling 19 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20q13.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS19.

• GAIP
• RGSGAIP

Llyfryddiaeth

• "RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling. ". Cancer Lett. 2011. PMID 21705135.
• "Solution structure of human GAIP (Galpha interacting protein): a regulator of G protein signaling. ". J Mol Biol. 1999. PMID 10452897.
• "RGS19 converts iron deprivation stress into a growth-inhibitory signal. ". Biochem Biophys Res Commun. 2015. PMID 26116529.
• "5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. ". Cell Signal. 2014. PMID 24793302.
• "Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum.". Mol Cell Biochem. 2012. PMID 22045062.