RGS14

RGS14
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JNU, 2OM2, 2XNS, 3ONW, 3QI2
Dynodwyr
Cyfenwau	RGS14, regulator of G protein signaling 14
Dynodwyr allanol	OMIM: 602513 HomoloGene: 4735 GeneCards: RGS14
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GTPase activating protein binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • GO:0005083 GTPase regulator activity • microtubule binding • GO:0001948, GO:0016582 protein binding • GDP-dissociation inhibitor activity • G-protein alpha-subunit binding • signaling receptor complex adaptor activity • protein kinase binding • GO:0006184 GTPase activity Cydrannau o'r gell • cytoplasm • PML body • centrosome • postsynaptic membrane • cell projection • spindle pole • nuclear body • bilen • GO:0097483, GO:0097481 postsynaptic density • Cellbilen • spindle • dendritic spine • synapse • microtubule organizing center • cell junction • dendrite • microtubule • Cytosgerbwd • cnewyllyn cell • glutamatergic synapse Prosesau biolegol • visual learning • GO:0007243 intracellular signal transduction • regulation of G protein-coupled receptor signaling pathway • chromosome segregation • learning • GO:0001306 response to oxidative stress • Cellraniad • positive regulation of neurogenesis • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • GO:0043146 spindle organization • long-term memory • negative regulation of MAP kinase activity • nucleocytoplasmic transport • zygote asymmetric cell division • negative regulation of ERK1 and ERK2 cascade • cell cycle • platelet-derived growth factor receptor signaling pathway • negative regulation of signal transduction • regulation of DNA-templated transcription in response to stress • negative regulation of synaptic plasticity • GO:0072468 signal transduction • long-term potentiation • GO:0007067 Mitosis • negative regulation of G protein-coupled receptor signaling pathway • modulation of chemical synaptic transmission • G protein-coupled receptor signaling pathway • positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10636	n/a
Ensembl	ENSG00000169220	n/a
UniProt	O43566	n/a
RefSeq (mRNA)	NM_006480 NM_001366617 NM_001366618	n/a
RefSeq (protein)	NP_006471 NP_001353546 NP_001353547	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS14 yw RGS14 a elwir hefyd yn Regulator of G protein signaling 14 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q35.3.

Llyfryddiaeth

• "Regulator of G-protein signaling 14 protein modulates Ca²+ influx through Cav1 channels. ". Neuroreport. 2010. PMID 20842066.
• "RGS14 is a microtubule-associated protein. ". Cell Cycle. 2005. PMID 15917656.
• "The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins. ". J Cell Biochem. 2013. PMID 23255434.
• "Backbone and sidechain 1H, 13C and 15N resonance assignments of the RGS domain from human RGS14. ". Biomol NMR Assign. 2007. PMID 19636837.
• "RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways.". Mol Pharmacol. 2000. PMID 10953050.