RGL2

RGL2
Dynodwyr
Cyfenwau	RGL2, HKE1.5, KE1.5, RAB2L, ral guanine nucleotide dissociation stimulator like 2
Dynodwyr allanol	OMIM: 602306 HomoloGene: 3494 GeneCards: RGL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • guanyl-nucleotide exchange factor activity Cydrannau o'r gell • intracellular anatomical structure • cydran cellog Prosesau biolegol • small GTPase mediated signal transduction • Ras protein signal transduction • GO:0072468 signal transduction • negative regulation of cardiac muscle cell apoptotic process • regulation of Ral protein signal transduction • positive regulation of phosphatidylinositol 3-kinase signaling • regulation of molecular function Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5863	n/a
Ensembl	ENSG00000228736 ENSG00000237441 ENSG00000237825 ENSG00000224841 ENSG00000206282 n/a	n/a
UniProt	O15211	n/a
RefSeq (mRNA)	NM_001243738 NM_004761	n/a
RefSeq (protein)	NP_001230667 NP_004752	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGL2 yw RGL2 a elwir hefyd yn Ral guanine nucleotide dissociation stimulator-like 2 a Ral guanine nucleotide dissociation stimulator like 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.32.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGL2.

• KE1.5
• RAB2L
• HKE1.5

Llyfryddiaeth

• "Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms. ". J Biol Chem. 2010. PMID 20801877.
• "Functional characterization of SAMD9, a protein deficient in normophosphatemic familial tumoral calcinosis. ". J Invest Dermatol. 2011. PMID 21160498.
• "G-protein binding features and regulation of the RalGDS family member, RGL2. ". Biochem J. 2008. PMID 18540861.
• "cDNA cloning, northern hybridization, and mapping analysis of a putative GDS-related protein gene at the centromeric ends of the human and mouse MHC regions. ". Immunogenetics. 1999. PMID 10079301.
• "Isolation and mapping of RAB2L, a human cDNA that encodes a protein homologous to RalGDS.". Cytogenet Cell Genet. 1996. PMID 8976381.